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    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title Crystal structures of 2-methylisocitrate lyase in complex with product and with isocitrate inhibitor provide insight into lyase substrate specificity, catalysis and evolution. Biochemistry 44 2949-2962 2005
    Site S2F
    PDB Id 1oqf Target Id prpB
    Molecular Characteristics
    Alias Ids TPS14880, Molecular Weight 32132.83 Da.
    Residues 296 Isoelectric Point 5.44
    Sequence mslhspgkafraaltkenplqivgtinanhallaqragyqaiylsgggvaagslglpdlgistlddvlt dirritdvcslpllvdadigfgssafnvartvksmikagaaglhiedqvgakrcghrpnkaivskeemv driraavdaktdpdfvimartdalavegldaaieraqayveagaemlfpeaitelamyrqfadavqvpi lanitefgatplfttdelrsahvamalyplsaframnraaehvynvlrqegtqksvidtmqtrnelyes inyyqyeekldnlfarsqvk
      BLAST   FFAS

    Structure Determination
    Method XRAY Chains 2
    Resolution (Å) 1.93 Rfree 0.247
    Matthews' coefficent 2.59 Rfactor 0.191
    Waters 648 Solvent Content 52.54

    Ligand Information


    Google Scholar output for 1oqf

    Protein Summary

    Ligand Summary




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