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3ckx

    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title Crystal structure of sterile 20-like kinase 3 (MST3, STK24) in complex with staurosporine. To be Published
    Site NYSGXRC
    PDB Id 3ckx Target Id
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    Related PDB Ids 3ckw 
    Molecular Characteristics
    Source
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    Alias Ids
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    TPS8056,PF00069, NP_003567.2
    Molecular Weight
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    Da.
    Residues
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    Isoelectric Point
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    Sequence
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      BLAST   FFAS

    Structure Determination
    Method XRAY
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    Chains 1
    Resolution (Å)
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    Rfree
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    Matthews' coefficent 2.08 Rfactor 0.204
    Waters
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    Solvent Content 40.84

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    Ligand Information
    Ligands STU (STAUROSPORINE) x 1
    Metals

    Jmol

     
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    Google Scholar output for 3ckx
    1. Selective antagonism of anticancer drugs for side-effect removal
    A Fernndez, S Sessel - Trends in pharmacological sciences, 2009 - Elsevier
     
    2. Structural comparison of human mammalian ste20-like kinases
    CJ Record, A Chaikuad, P Rellos, S Das, ACW Pike - PloS one, 2010 - dx.plos.org
     
    3. Structures of human MST3 kinase in complex with adenine, ADP and Mn2+
    TP Ko, WY Jeng, CI Liu, MD Lai, CL Wu - Section D: Biological , 2010 - scripts.iucr.org
     
    4. Analysis of conditions affecting auto-phosphorylation of human kinases during expression in bacteria
    A Shrestha, G Hamilton, E O'Neill, S Knapp - Protein expression and , 2011 - Elsevier
     
    5. Conserved Core Substructures in the Overlay of Protein-Ligand Complexes
    BC Finzel, R Akavaram, A Ragipindi - Journal of chemical , 2011 - ACS Publications
     
    6. Fragment screening of cyclin G-associated kinase by weak affinity chromatography
    E Meiby, S Knapp, JM Elkins, S Ohlson - Analytical and Bioanalytical , 2012 - Springer
     

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    Protein Summary


    Ligand Summary

    Reviews

    References

     

    No references found.

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