The Open Protein Structure Annotation Network
PDB Keyword


    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title Crystal structure of an adenine deaminase. TO BE PUBLISHED
    Site NYSGXRC
    PDB Id 2ics Target Id NYSGXRC-9295a
    Molecular Characteristics
    Source Enterococcus faecalis
    Alias Ids TPS7812,29375425, PF01979 Molecular Weight 40656.18 Da.
    Residues 369 Isoelectric Point 5.10
    Sequence mdydllikngqtvngmpveiaikekkiaavaatisgsaketihlepgtyvsagwiddhvhcfekmalyy dypdeigvkkgvttvidagttgaenihefydlaqqaktnvfglvniskwgivaqdeladlskvqaslvk kaiqelpdfvvgikarmsrtvigdngitplelakqiqqenqeiplmvhigsapphldeilalmekgdvl thcfngkengildqatdkikdfawqaynkgvvfdighgtdsfnfhvaetalregmkaasistdiyirnr engpvydlattmeklrvvgydwpeiiekvtkapaenfhltqkgtleigkdadltiftiqaeektltdsn gltrvakeqirpiktiiggqiydn
      BLAST   FFAS

    Structure Determination
    Method XRAY Chains 1
    Resolution (Å) 2.30 Rfree 0.239
    Matthews' coefficent 2.48 Rfactor 0.198
    Waters 108 Solvent Content 50.30

    Ligand Information
    Ligands ADE (ADENINE) x 1
    Metals ZN (ZINC) x 2


    Google Scholar output for 2ics
    1. Target selection and annotation for the structural genomics of the amidohydrolase and enolase superfamilies
    U Pieper, R Chiang, JJ Seffernick, SD Brown - Journal of structural and , 2009 - Springer
    2. Structure of dihydropyrimidinase from Sinorhizobium meliloti CECT4114: New features in an amidohydrolase family member
    S Martnez-Rodrguez, AI Martnez-Gmez - Journal of structural , 2010 - Elsevier
    3. Aminohydrolases acting on adenine, adenosine and their derivatives
    H Pospisilova, I Frebort - BIOMEDICAL PAPERS-PALACKY , 2007 - biomed.papers.upol.cz
    4. Catalytic mechanism and three-dimensional structure of adenine deaminase
    SS Kamat, A Bagaria, D Kumaran - Biochemistry, 2011 - ACS Publications
    5. Reversible post-translational carboxylation modulates the enzymatic activity of N-acetyl-L-ornithine transcarbamylase
    Y Li, X Yu, J Ho, D Fushman, N Allewell - Biochemistry, 2010 - ACS Publications

    Protein Summary

    Ligand Summary




    No references found.

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