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2hy3

    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title Structural genomics of protein phosphatases. J.STRUCT.FUNCT.GENOM. 8 121-140 2007
    Site NYSGXRC
    PDB Id 2hy3 Target Id NYSGXRC-8615a
    Related PDB Ids 2pbn 
    Molecular Characteristics
    Source Homo sapiens
    Alias Ids TPS7905,PF00102, NP_002832 Molecular Weight 162050.09 Da.
    Residues 1445 Isoelectric Point 6.02
    Sequence mrrllepcwwilflkitssvlhyvvcfpaltegyvgalhenrhgsavqirrrkasgdpywaysgaygpe hwvtssvscgsrhqspidildqyarvgeeyqelqldgfdnessnktwmkntgktvaillkddyfvsgag lpgrfkaekvefhwghsngsagsehsingrrfpvemqiffynpddfdsfqtaisenriigamaiffqvs prdnsaldpiihglkgvvhheketfldpfvlrdllpaslgsyyrytgslttppcseivewivfrrpvpi syhqleafysiftteqqdhvksveylrnnfrpqqrlhdrvvsksavrdswnhdmtdflenplgteaskv cssppihmkvqplnqtalqvswsqpetiyhppimnymisyswtknedekektftkdsdkdlkatishvs pdslylfrvqavcrndmrsdfsqtmlfqanttrifqgtrivktgvptaspassadmapissgsstwtss gipfsfvsmatgmgpsssgsqatvasvvtstllaglgfggggissfpstvwptrlptaasaskqaarpv lattealaspgpdgdssptkdgegteegekdeksesedgereheedgekdsekkeksgvthaaeernqt epsptpsspnrtaegghqtipgheqdhtavptdqtggrrdagpgldpdmvtstqvpptateeqyagsdp krpempskkpmsrgdrfsedsrfitvnpaekntsgmisrpapgrmewiiplivvsaltfvclilliavl vywrgcnkikskgfprrfrevpssgergekgsrkcfqtahfyvedsssprvvpnesipiipipddmeai pvkqfvkhigelysnnqhgfsedfeevqrctadmnitaehsnhpenkhknryinilaydhsrvklrplp gkdskhsdyinanyvdgynkakayiatqgplkstfedfwrmiweqntgiivmitnlvekgrrkcdqywp tenseeygniivtlkstkihacytvrrfsirntkvkkgqkgnpkgrqnervviqyhytqwpdmgvpeya lpvltfvrrssaarmpetgpvlvhcsagvgrtgtyividsmlqqikdkstvnvlgflkhirtqrnylvq teeqyifihdalleailgketevssnqlhsyvnsilipgvggktrlekqfklvtqcnakyvecfsaqke cnkeknrnssvvpserarvglaplpgmkgtdyinasyimgyyrsnefiitqhplphttkdfwrmiwdhn aqiivmlpdnqslaedefvywpsreesmnceaftvtliskdrlclsneeqiiihdfileatqddyvlev rhfqcpkwpnpdapisstfelinvikeealtrdgptivhdeygavsagmlcalttlsqqlenenavdvf qvakminlmrpgvftdieqyqfiykarlslvstkengngpmtvdkngavliadesdpaesmeslv
      BLAST   FFAS

    Structure Determination
    Method XRAY Chains 2
    Resolution (Å) 2.60 Rfree 0.28796
    Matthews' coefficent 2.42 Rfactor 0.20151
    Waters 50 Solvent Content 49.09

    Ligand Information
    Ligands VO4 (VANADATE) x 2
    Metals

    Jmol

     
    Google Scholar output for 2hy3
    1. Structural genomics of protein phosphatases
    SC Almo, JB Bonanno, JM Sauder, S Emtage - Journal of structural and , 2007 - Springer
     
    2. Small Molecule Receptor Protein Tyrosine Phosphatase (RPTP ) Ligands That Inhibit Phosphatase Activity via Perturbation of the Tryptophan-Proline-Aspartate (
    S Sheriff, BR Beno, W Zhai, WA Kostich - Journal of medicinal , 2011 - ACS Publications
     

    Protein Summary


    Ligand Summary

    Reviews

    References

     

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