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    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title Crystal Structure of the MazE/MazF Complex. Molecular Bases of Antidote-Toxin Recognition. Mol.Cell 11 875-884 2003
    Site NYSGXRC
    PDB Id 1ub4 Target Id NYSGXRC-T1468
    Molecular Characteristics
    Source Escherichia coli
    Alias Ids TPS8170,126777 Molecular Weight 33542.97 Da.
    Residues 305 Isoelectric Point 6.27
    Sequence vsryvpdmgdliwvdfdptkgseqaghrpavvlspfmynnktgmclcvpcttqskgypfevvlsgqerd gvaladqvksiawrargatkkgtvapeelqlikakinvligvsryvpdmgdliwvdfdptkgseqaghr pavvlspfmynnktgmclcvpcttqskgypfevvlsgqerdgvaladqvksiawrargatkkgtvapee lqlikakinvliggphmihssvkrwgnspavripatlmqalnlniddevkidlvdgkliiepvrkepvf tlaelvnditpenlhenidwgepkdkevw
      BLAST   FFAS

    Structure Determination
    Method XRAY Chains 1
    Resolution (Å) 1.70 Rfree 0.232
    Matthews' coefficent 2.49 Rfactor 0.21
    Waters 199 Solvent Content 50.55

    Ligand Information


    Google Scholar output for 1ub4
    1. Crystal Structure of the MazE/MazF Complex:: Molecular Bases of Antidote-Toxin Recognition
    K Kamada, F Hanaoka, SK Burley - Molecular cell, 2003 - Elsevier
    2. An antisense RNA controls synthesis of an SOS_induced toxin evolved from an antitoxin
    M Kawano, L Aravind, G Storz - Molecular microbiology, 2007 - Wiley Online Library
    3. prlF and yhaV encode a new toxin-antitoxin system in Escherichia coli
    O Schmidt, VJ Schuenemann, NJ Hand - Journal of molecular , 2007 - Elsevier
    4. Shutdown decay of mRNA
    C Condon - Molecular microbiology, 2006 - Wiley Online Library
    5. The Bacillus subtilis ydcDE operon encodes an endoribonuclease of the MazF/PemK family and its inhibitor
    O Pellegrini, N Mathy, A Gogos, L Shapiro - Molecular , 2005 - Wiley Online Library
    6. AbrB-like transcription factors assume a swapped hairpin fold that is evolutionarily related to double-psi _ barrels
    M Coles, S Djuranovic, J Sding, T Frickey, K Koretke - Structure, 2005 - Elsevier
    7. Revised structure of the AbrB N-terminal domain unifies a diverse superfamily of putative DNA-binding proteins
    BG Bobay, A Andreeva, GA Mueller, J Cavanagh - FEBS letters, 2005 - Elsevier
    8. Mutagenesis-based definitions and probes of residue burial in proteins
    K Bajaj, P Chakrabarti - Proceedings of the , 2005 - National Acad Sciences
    9. Characterization of Dual Substrate Binding Sites in the Homodimeric Structure of Escherichia coli mRNA Interferase MazF
    GY Li, Y Zhang, MCY Chan, TK Mal, KP Hoeflich - Journal of molecular , 2006 - Elsevier
    10. Structure and function of bacterial kid-kis and related toxin-antitoxin systems
    MB Kamphuis, M Chiara Monti - Protein and Peptide , 2007 - ingentaconnect.com
    11. Structural and thermodynamic characterization of the Escherichia coli RelBE toxin-antitoxin system: indication for a functional role of differential stability
    I Cherny, M Overgaard, J Borch, Y Bram, K Gerdes - Biochemistry, 2007 - ACS Publications
    12. Toxin-antitoxin systems in bacteria and archaea
    Y Yamaguchi, JH Park, M Inouye - Annual review of genetics, 2011 - annualreviews.org
    13. Interactions between the toxin Kid of the bacterial parD system and the antitoxins Kis and MazE
    MB Kamphuis, MC Monti - PROTEINS: , 2007 - Wiley Online Library
    14. parD toxinantitoxin system of plasmid R1basic contributions, biotechnological applications and relationships with closely_related toxinantitoxin systems
    E Diago_Navarro, AM Hernandez_Arriaga - Febs , 2010 - Wiley Online Library
    15. Prokaryotic toxin-antitoxin systemsthe role in bacterial physiology and application in molecular biology
    M Bukowski, A Rojowska, B Wladyka - Acta Biochim Pol, 2011 - ptbioch.edu.pl
    16. Crystal structure of the DNA-bound VapBC2 antitoxin/toxin pair from Rickettsia felis
    MJ Mat, R Vincentelli, N Foos, D Raoult - Nucleic Acids , 2011 - Oxford Univ Press
    17. Structural Models of Protein-DNA Complexes Based on Interface Prediction and Docking
    S Qin, HX Zhou - Current Protein and Peptide Science, 2011 - ingentaconnect.com
    18. Amino-acid-dependent main-chain torsion-energy terms for protein systems
    Y Sakae, Y Okamoto - Arxiv preprint arXiv:1206.3909, 2012 - arxiv.org
    19. Optimizations of protein force fields
    Y Sakae, Y Okamoto - Arxiv preprint arXiv:1208.6150, 2012 - arxiv.org
    AL Jochim, PS Arora - US Patent App. 12/753,638, 2010 - Google Patents

    Protein Summary

    Ligand Summary




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