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    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title Crystal structure of hypothetical transcriptional regulator ycdC from Escherichia coli. To be Published
    Site NYSGXRC
    PDB Id 1pb6 Target Id NYSGXRC-T803
    Molecular Characteristics
    Source Escherichia coli.
    Alias Ids TPS8136,P75899 Molecular Weight 23686.29 Da.
    Residues 212 Isoelectric Point 8.92
    Sequence mtqgavkttgkrsravsakkkailsaaldtfsqfgfhgtrleqiaelagvsktnllyyfpskealyiav lrqildiwlaplkafredfaplaaikeyirlklevsrdypqasrlfcmemlagapllmdeltgdlkali deksaliagwvksgklapidpqhlifmiwastqhyadfapqveavtgatlrdevffnqtvenvqriiie girpr
      BLAST   FFAS

    Structure Determination
    Method XRAY Chains 4
    Resolution (Å) 2.50 Rfree 0.277
    Matthews' coefficent 3.15 Rfactor 0.238
    Waters 160 Solvent Content 60.60

    Ligand Information


    Google Scholar output for 1pb6
    1. Crystal Structure of the TetR/CamR Family Repressor Mycobacterium tuberculosis EthR Implicated in Ethionamide Resistance
    LG Dover, PE Corsino, IR Daniels, SL Cocklin - Journal of molecular , 2004 - Elsevier
    2. A comprehensive analysis of structural and sequence conservation in the TetR family transcriptional regulators
    Z Yu, SE Reichheld, A Savchenko, J Parkinson - Journal of molecular , 2010 - Elsevier
    3. Walking through the protein sequence space: Towards new generation of the homology modeling
    ZM Frenkel, EN Trifonov - PROTEINS: Structure, Function, and , 2007 - Wiley Online Library
    4. Crystal Structure of Bacillus cereus HlyIIR, a Transcriptional Regulator of the Gene for Pore-forming Toxin Hemolysin II
    OV Kovalevskiy, AA Lebedev, AK Surin - Journal of molecular , 2007 - Elsevier
    5. Unmet challenges of structural genomics
    M Chruszcz, M Domagalski, T Osinski - Current opinion in , 2010 - Elsevier
    6. Saccharomyces cerevisiae Hop1 protein zinc finger motif binds to the Holliday junction and distorts the DNA structure: implications for holliday junction migration
    P Tripathi, D Pal, K Muniyappa - Biochemistry, 2007 - ACS Publications
    7. The proteinDNA contacts in RutR carAB operator complexes
    PN Le Minh, I Bervoets, D Maes - Nucleic acids , 2010 - Oxford Univ Press
    8. X-ray crystallography: assessment and validation of protein-small molecule complexes for drug discovery
    DR Cooper, PJ Porebski - Expert Opinion on , 2011 - informahealthcare.com
    9. Protein structure prediction based on the sliced lattice model
    CC Wang, CB Yang, HY Ann - 2008 Conference on , 2005 - etd.lib.nsysu.edu.tw
    10. New insights into the structure, function and evolution of TETR family transcriptional regulators
    Z Yu - 2010 -
    NC BENSON, V DAGGETT - Journal of Bioinformatics and , 2012 - World Scientific
    12. Unmet challenges of structural genomics
    A Wlodawer, W Minor - Current Opinion in Structural Biology, 2010 - mcl1.ncifcrf.gov
    13. Prediction of Protein Backbone Based on the Sliced Lattice Model
    CC Wang, CB Yang, HY Ann, HY Chang - 2008 - csie.npu.edu.tw
    14. Multi-Scale Genetics towards Understanding the Hierarchy of Transcription Factor Network in Genome Regulation
    A Ishihama, H Ogasawara, T Shimada - and Human Science , 2006 - ieeexplore.ieee.org

    Protein Summary


    Ligand Summary




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