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The Open Protein Structure Annotation Network
PDB Keyword
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2rde

    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title The structural basis of cyclic diguanylate signal transduction by PilZ domains. Embo J. 26 5153-5166 2007
    Site NESGC
    PDB Id 2rde Target Id
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    Molecular Characteristics
    Source
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    Alias Ids
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    TPS9229,2.30.110.10, 2.40.10.220, PF07238
    Molecular Weight
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    Da.
    Residues
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    Isoelectric Point
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    Sequence
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      BLAST   FFAS

    Structure Determination
    Method XRAY
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    Chains 2
    Resolution (Å)
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    Rfree
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    Matthews' coefficent 2.48 Rfactor 0.195
    Waters
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    Solvent Content 50.42

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    Ligand Information
    Ligands C2E (9,9'-[(2R,3R,3AS,5S,7AR,9R,10R,10AS,12S,14AR)-3,5,10,) x 2
    Metals

    Jmol

     
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    Google Scholar output for 2rde
    1. Catalytic mechanism of cyclic di-GMP-specific phosphodiesterase: a study of the EAL domain-containing RocR from Pseudomonas aeruginosa
    F Rao, Y Yang, Y Qi, ZX Liang - Journal of bacteriology, 2008 - Am Soc Microbiol
     
    2. The cAMP receptor-like protein CLP is a novel c-di-GMP receptor linking cell-cell signaling to virulence gene expression in Xanthomonas campestris
    KH Chin, YC Lee, ZL Tu, CH Chen, YH Tseng - Journal of molecular , 2010 - Elsevier
     
    3. Structural basis for c-di-GMP-mediated inside-out signaling controlling periplasmic proteolysis
    MVAS Navarro, PD Newell, PV Krasteva, D Chatterjee - PLoS biology, 2011 - dx.plos.org
     
    4. Structure of PP4397 reveals the molecular basis for different c-di-GMP binding modes by Pilz domain proteins
    J Ko, KS Ryu, H Kim, JS Shin, JO Lee - Journal of molecular , 2010 - Elsevier
     
    5. PILZ protein structure and interactions with PILB and the FIMX EAL domain: implications for control of type IV pilus biogenesis
    CR Guzzo, RK Salinas, MO Andrade - Journal of molecular , 2009 - Elsevier
     
    6. XC1028 from Xanthomonas campestris adopts a PilZ domain_like structure without ac_di_GMP switch
    TN Li, KH Chin, JH Liu, AHJ Wang - Structure, Function, and , 2009 - Wiley Online Library
     
    7. A Novel Tetrameric PilZ Domain Structure from Xanthomonads
    TN Li, KH Chin, KM Fung, MT Yang, AHJ Wang - PloS one, 2011 - dx.plos.org
     
    8. Base ionization and ligand binding: how small ribozymes and riboswitches gain a foothold in a protein world
    JA Liberman, JE Wedekind - Current Opinion in Structural Biology, 2011 - Elsevier
     
    9. Stability and Dynamics of Cyclic Diguanylic Acid in Solution
    L Zhang, M Meuwly - ChemPhysChem, 2011 - Wiley Online Library
     
    10. Crystal structure of a catalytically active GG (D/E) EF diguanylate cyclase domain from Marinobacter aquaeolei with bound c-di-GMP product
    SM Vorobiev, H Neely, B Yu, J Seetharaman - Journal of structural and , 2012 - Springer
     
    11. Solution Structure of the PilZ Domain Protein PA4608 Complex with Cyclic di-GMP Identifies Charge Clustering as Molecular Readout
    J Habazettl, MG Allan, U Jenal, S Grzesiek - Journal of Biological Chemistry, 2011 - ASBMB
     
    12. Sensing the messenger: The diverse ways that bacteria signal through c_di_GMP
    PV Krasteva, KM Giglio, H Sondermann - Protein Science, 2012 - Wiley Online Library
     

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    Protein Summary


    Ligand Summary

    Reviews

    References

     

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