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    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title Molecular basis of Pirh2-mediated p53 ubiquitylation. Nat.Struct.Mol.Biol. 15 1334-1342 2008
    Site NESGC
    PDB Id 2jrj Target Id HT2B
    Molecular Characteristics
    Source Homo sapiens
    Alias Ids TPS8928,, PF00097, 15333 Molecular Weight 5935.63 Da.
    Residues 51 Isoelectric Point 6.56
    Sequence envsrqncpicledihtsrvvahvlpcghllhrtcyeemlkegyrcplcmh
      BLAST   FFAS

    Structure Determination
    Method NMR Chains 1

    Ligand Information
    Metals ZN (ZINC) x 2


    Google Scholar output for 2jrj
    1. Molecular basis of Pirh2-mediated p53 ubiquitylation
    Y Sheng, RC Laister, A Lemak, B Wu, E Tai - Nature structural & , 2008 - nature.com
    2. RING finger E3 ubiquitin ligases: structure and drug discovery
    CT Chasapis, GA Spyroulias - Current pharmaceutical design, 2009 - ingentaconnect.com
    3. Bi-directional SIFT predicts a subset of activating mutations
    W Lee, Y Zhang, K Mukhyala, RA Lazarus, Z Zhang - PloS one, 2009 - dx.plos.org
    4. NMR_based insights into the conformational & interaction properties of Arkadia RING_H2 E3 Ub ligase
    CT Chasapis, NG Kandias, V Episkopou - Proteins: Structure, , 2012 - Wiley Online Library

    Protein Summary

    Ligand Summary




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