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    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title NMR structure and binding studies confirm that PA4608 from Pseudomonas aeruginosa is a PilZ domain and a c-di-GMP binding protein. Proteins 66 266-271 2007
    Site NESGC
    PDB Id 1ywu Target Id PaT7
    Molecular Characteristics
    Source Pseudomonas aeruginosa
    Alias Ids TPS9008,PF07238,, 6514 Molecular Weight 14572.59 Da.
    Residues 125 Isoelectric Point 4.78
    Sequence msdqhderrrfhriafdadseilqgerrwevllhdvslhgilvgqpqdwngdpqrpfearlylgldvli rmeislawardgllgfecqhidldsishlrrlvelnlgdeellerelallvsahdd
      BLAST   FFAS

    Structure Determination
    Method NMR Chains 1

    Ligand Information


    Google Scholar output for 1ywu
    1. PilZ domain is part of the bacterial c-di-GMP binding protein
    D Amikam, MY Galperin - Bioinformatics, 2006 - Oxford Univ Press
    2. DgrA is a member of a new family of cyclic diguanosine monophosphate receptors and controls flagellar motor function in Caulobacter crescentus
    M Christen, B Christen, MG Allan - Proceedings of the , 2007 - National Acad Sciences
    3. The structural basis of cyclic diguanylate signal transduction by PilZ domains
    J Benach, SS Swaminathan, R Tamayo - The EMBO , 2007 - nature.com
    4. Diversity of structure and function of response regulator output domains
    MY Galperin - Current opinion in microbiology, 2010 - Elsevier
    5. NMR structure and binding studies confirm that PA4608 from Pseudomonas aeruginosa is a PilZ domain and ac_di_GMP binding protein
    TA Ramelot, A Yee, JR Cort, A Semesi - Proteins: Structure, , 2007 - Wiley Online Library
    6. Alg44, a unique protein required for alginate biosynthesis in Pseudomonas aeruginosa
    U Remminghorst, BHA Rehm - FEBS letters, 2006 - Elsevier
    7. PILZ protein structure and interactions with PILB and the FIMX EAL domain: implications for control of type IV pilus biogenesis
    CR Guzzo, RK Salinas, MO Andrade - Journal of molecular , 2009 - Elsevier
    8. Conserved structural determinants in three_fingered protein domains
    A Galat, G Gross, P Drevet, A Sato, A Mnez - FEBS Journal, 2008 - Wiley Online Library
    9. Solution Structure of the PilZ Domain Protein PA4608 Complex with Cyclic di-GMP Identifies Charge Clustering as Molecular Readout
    J Habazettl, MG Allan, U Jenal, S Grzesiek - Journal of Biological Chemistry, 2011 - ASBMB
    10. XC1028 from Xanthomonas campestris adopts a PilZ domain_like structure without ac_di_GMP switch
    TN Li, KH Chin, JH Liu, AHJ Wang - Structure, Function, and , 2009 - Wiley Online Library
    11. Structural characterization reveals that a PilZ domain protein undergoes substantial conformational change upon binding to cyclic dimeric guanosine monophosphate
    JS Shin, KS Ryu, J Ko, A Lee, BS Choi - Protein Science, 2011 - Wiley Online Library
    12. A Novel Tetrameric PilZ Domain Structure from Xanthomonads
    TN Li, KH Chin, KM Fung, MT Yang, AHJ Wang - PloS one, 2011 - dx.plos.org
    13. Principles of c-di-GMP signaling: characterization of a second messenger system orchestrating bacterial life style
    B Christen - 2007 - edoc.unibas.ch
    14. Top (Index), File: 18034161. pdf
    C Sensitive, J Benach - The EMBO , 2007 - www-tsujii.is.su-tokyo.ac.jp
    15. XC6012 from Xanthomonas campestris Adopts a Novel Tetrameric PilZ Domain Structure Stabilized by a Central Parallel Four-Stranded Coiled-Coil
    TN Li, KH Chin, HJW Andrew - __________, 2009 - research.nchu.edu.tw
    16. Sensing the messenger: The diverse ways that bacteria signal through c_di_GMP
    PV Krasteva, KM Giglio, H Sondermann - Protein Science, 2012 - Wiley Online Library

    Protein Summary

    Ligand Summary




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