The Open Protein Structure Annotation Network
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    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title The 2.35 A structure of the TenA homolog from Pyrococcus furiosus supports an enzymatic function in thiamine metabolism. Acta Crystallogr.,Sect.D 61 589-598 2005
    Site NESGC
    PDB Id 1rtw Target Id PfR34
    Molecular Characteristics
    Source Pyrococcus furiosus
    Alias Ids TPS9018,PF03070, 1.20.910.10 Molecular Weight 25422.77 Da.
    Residues 212 Isoelectric Point 5.18
    Sequence mfseelikeneniwrrflphkfliemaentikkenfekwlvndyyfvknalrfmallmakapddllpff aesiyyiskelemfekkaqelgislngeidwraksyvnyllsvaslgsflegftalyceekayyeawkw vrenlkerspyqefinhwssqefgeyvkriekilnslaekhgefekerarevfkevskfelifwdiayg gegnv
      BLAST   FFAS

    Structure Determination
    Method XRAY Chains 4
    Resolution (Å) 2.35 Rfree 0.281
    Matthews' coefficent 2.40 Rfactor 0.24
    Waters 234 Solvent Content 48.67

    Ligand Information


    Google Scholar output for 1rtw
    1. Mass fractal dimension and the compactness of proteins
    MB Enright, DM Leitner - Physical Review E, 2005 - APS
    2. Structural characterization of the regulatory proteins TenA and TenI from Bacillus subtilis and identification of TenA as a thiaminase II
    V Angela, AL Haas, JH Park, TP Begley, SE Ealick - Biochemistry, 2005 - ACS Publications
    3. Ligands in PSI structures
    A Kumar, HJ Chiu, HL Axelrod, A Morse - Section F: Structural , 2010 - scripts.iucr.org
    4. The 2.35 A structure of the TenA homolog from Pyrococcus furiosus supports an enzymatic function in thiamine metabolism
    J Benach, WC Edstrom, I Lee, K Das - Section D: Biological , 2005 - scripts.iucr.org
    5. Structural and mutational analysis of TenA protein (HP1287) from the Helicobacter pylori thiamin salvage pathwayevidence of a different substrate specificity
    N Barison, L Cendron, A Trento, A Angelini - FEBS , 2009 - Wiley Online Library
    6. Engineering aluminum binding affinity in an isolated EF-hand from troponin C: A computational site-directed mutagenesis study
    RE Bongini, SB Culver, KM Elkins - Journal of inorganic biochemistry, 2007 - Elsevier
    7. Structure of trifunctional THI20 from yeast
    JB French, TP Begley, SE Ealick - Acta Crystallographica Section D: , 2011 - scripts.iucr.org
    8. Mathematical Modeling and Screening of Ligand Binding Sites in Protein using the Tetrahedral Motif Method and Double-Centroid Representation
    VM Reyes - 2012 - ritdml.rit.edu
    9. Protein Structure Database for Structural Genomics Group
    JY Lau - 2005 - www-nmr.cabm.rutgers.edu

    Protein Summary

    Ligand Summary




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