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The Open Protein Structure Annotation Network
PDB Keyword
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3ckd

    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases. Nat.Struct.Mol.Biol. 15 1293-1301 2008
    Site MCSG
    PDB Id 3ckd Target Id
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    Molecular Characteristics
    Source
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    Alias Ids
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    TPS5109,NP_858398.2, 198214
    Molecular Weight
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    Da.
    Residues
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    Isoelectric Point
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    Sequence
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      BLAST   FFAS

    Structure Determination
    Method XRAY
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    Chains 1
    Resolution (Å)
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    Rfree
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    Matthews' coefficent 2.75 Rfactor 0.2281
    Waters
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    Solvent Content 55.24

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    Ligand Information
    Ligands SO4 (SULFATE) x 2;GOL (GLYCEROL) x 3;PEG (DI(HYDROXYETHYL)ETHER) x 1
    Metals

    Jmol

     
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    Google Scholar output for 3ckd
    1. Structure of a Shigella effector reveals a new class of ubiquitin ligases
    Y Zhu, H Li, L Hu, J Wang, Y Zhou, Z Pang - Nature structural & , 2008 - nature.com
     
    2. Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases
    AU Singer, JR Rohde, R Lam, T Skarina - Nature structural & , 2008 - nature.com
     
    3. Hijacking the host ubiquitin pathway: structural strategies of bacterial E3 ubiquitin ligases
    SW Hicks, JE Galn - Current opinion in microbiology, 2010 - Elsevier
     
    4. The many faces of the YopM effector from plague causative bacterium Yersinia pestis and its implications for host immune modulation
    V Soundararajan, N Patel, V Subramanian - Innate , 2011 - ini.sagepub.com
     
    5. A disulfide driven domain swap switches off the activity of Shigella IpaH9. 8 E3 ligase
    A Seyedarabi, JA Sullivan, C Sasakawa - FEBS letters, 2010 - Elsevier
     
    6. The orchestrators of Shigella flexneri infection
    A Seyedarabi - Crystallography Reviews, 2010 - Taylor & Francis
     
    7. Conserved Structural Mechanisms for Autoinhibition in IpaH Ubiquitin Ligases
    YC Chou, AFA Keszei, JR Rohde, M Tyers - Journal of Biological , 2012 - ASBMB
     

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    Protein Summary


    Ligand Summary

    Reviews

    References

     

    No references found.

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