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2okg

    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title Crystal structures of the effector-binding domain of repressor Central glycolytic gene Regulator from Bacillus subtilis reveal ligand-induced structural changes upon binding of several glycolytic intermediates. Mol.Microbiol. 69 895-910 2008
    Site MCSG
    PDB Id 2okg Target Id
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    Molecular Characteristics
    Source
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    Alias Ids
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    TPS5777,CAB15400.1, PF04198, 224308
    Molecular Weight
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    Da.
    Residues
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    Isoelectric Point
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    Sequence
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      BLAST   FFAS

    Structure Determination
    Method XRAY
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    Chains 2
    Resolution (Å)
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    Rfree
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    Matthews' coefficent 2.30 Rfactor 0.19575
    Waters
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    Solvent Content 46.56

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    Ligand Information
    Ligands G3H (GLYCERALDEHYDE-3-PHOSPHATE) x 1
    Metals CL (CHLORIDE) x 3

    Jmol

     
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    Google Scholar output for 2okg
    1. Fructose-1, 6-bisphosphate acts both as an inducer and as a structural cofactor of the central glycolytic genes repressor (CggR)
    S Zorrilla, D Chaix, A Ortega, C Alfonso, T Doan - Biochemistry, 2007 - ACS Publications
     
    2. A phospho_sugar binding domain homologous to NagB enzymes regulates the activity of the central glycolytic genes repressor
    T Doan, L Martin, S Zorrilla, D Chaix - Proteins: Structure, , 2008 - Wiley Online Library
     
    3. Crystal structures of the effector_binding domain of repressor Central glycolytic gene Regulator from Bacillus subtilis reveal ligand_induced structural changes upon
    P _ez_ov, M Koek, SF Moy - Molecular , 2008 - Wiley Online Library
     
    4. Crystal structure of the full-length sorbitol operon regulator SorC from Klebsiella pneumoniae: structural evidence for a novel transcriptional regulation mechanism
    D de Sanctis, CE McVey, FJ Enguita - Journal of molecular , 2009 - Elsevier
     
    5. Physical basis of the inducer-dependent cooperativity of the Central glycolytic genes Repressor/DNA complex
    D Chaix, ML Ferguson, C Atmanene - Nucleic acids , 2010 - Oxford Univ Press
     
    6. Dynamic features of homo_dimer interfaces calculated by normal mode analysis
    Y Tsuchiya, K Kinoshita, S Endo, H Wako - Protein Science, 2012 - Wiley Online Library
     

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    Protein Summary


    Ligand Summary

    Reviews

    References

     

    No references found.

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