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    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title Crystal Structures of Delta(1)-Pyrroline-5-carboxylate Reductase from Human Pathogens Neisseria meningitides and Streptococcus pyogenes. J.Mol.Biol. 354 91-106 2005
    Site MCSG
    PDB Id 2amf Target Id APC28530
    Related PDB Ids 2ahr 
    Molecular Characteristics
    Source Streptococcus pyogenes m1 gas
    Alias Ids TPS5410,AAK33229, 160490 Molecular Weight 27304.15 Da.
    Residues 256 Isoelectric Point 6.43
    Sequence mkigiigvgkmasaiikglkqtpheliisgsslerskeiaeqlalpyamshqdlidqvdlvilgikpql fetvlkplhfkqpiismaagislqrlatfvgqdlpllrimpnmnaqilqsstaltgnalvsqelqarvr dltdsfgstfdisekdfdtftalagsspayiylfiealakagvkngipkakaleivtqtvlasasnlkt ssqsphdfidaicspggttiaglmelerlgltatvssaidktidkaksl
      BLAST   FFAS

    Structure Determination
    Method XRAY Chains 5
    Resolution (Å) 2.20 Rfree 0.21542
    Matthews' coefficent 2.88 Rfactor 0.17333
    Waters 739 Solvent Content 57.00

    Ligand Information
    Ligands PRO x 10
    Metals NA (SODIUM) x 5


    Google Scholar output for 2amf
    1. Crystal structure of human pyrroline-5-carboxylate reductase
    Z Meng, Z Lou, Z Liu, M Li, X Zhao, M Bartlam - Journal of molecular , 2006 - Elsevier
    2. Structural biology of proline catabolism
    JJ Tanner - Amino acids, 2008 - Springer
    3. Crystal Structures of _ 1-Pyrroline-5-carboxylate Reductase from Human Pathogens Neisseria meningitides and Streptococcus pyogenes
    B Nocek, C Chang, H Li, L Lezondra, D Holzle - Journal of molecular , 2005 - Elsevier
    4. De-orphaning the structural proteome through reciprocal comparison of evolutionarily important structural features
    RM Ward, S Erdin, TA Tran, DM Kristensen - PloS one, 2008 - dx.plos.org
    5. Plant P5C reductase as a new target for aminomethylenebisphosphonates
    G Forlani, S Giberti, L Berlicki - Journal of agricultural , 2007 - ACS Publications
    6. Structure of an Amide Bond Forming F420:[gamma][gamma]-glutamyl Ligase from Archaeoglobus Fulgidus-A Member of a New Family of Non-ribosomal Peptide
    B Nocek, E Evdokimova, M Proudfoot - Journal of molecular , 2007 - Elsevier

    Protein Summary

    Ligand Summary




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