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PDB Keyword
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4djn

    Title Crystal structure of a ribonucleotide reductase M2 B (RNRR2) from Homo sapiens at 2.20 A resolution. To be published
    Site JCSG
    PDB Id 4djn Target Id
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    Molecular Characteristics
    Source
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    Alias Ids
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    TPS67252,NP_056528.2
    Molecular Weight
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    Da.
    Residues
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    Isoelectric Point
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    Sequence
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      BLAST   FFAS

    Structure Determination
    Method XRAY
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    Chains 2
    Resolution (Å)
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    Rfree
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    Matthews' coefficent 3.12 Rfactor 0.1931
    Waters
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    Solvent Content 60.57

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    Ligand Information
    Ligands
    Metals

    Jmol

     
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    Google Scholar output for 4djn

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    Protein Summary

    This is the structure of ribonucleotide reductase M2 B (TP53 inducible). NP_056528.2 belongs to PFAM PF00268 Ribonuc_red_sm.

    The structure is shown below.

    MA16109D.png

     

    There are numerous homologs of this structure, as shown by DALI search.

    Top 10 DALI Structural Homologs
     
    N PDB Z-score RMSD LALI NRES %ID Description
    1 1h0o 45.5 0.7 285 288 79 Ribonucleoside-diphosphate Reductase
    2 1xsm 45.2 0.8 286 288 79 Ribonucleotide Reductase R2
    3 1h0n 45.1 0.8 286 288 79 Ribonucleoside-diphosphate Reductase
    4 1w69 44.8 0.7 280 281 80 Ribonucleoside-diphosphate Reductase M2 Chain
    5 1w68 44.4 0.8 280 281 80 Ribonucleoside-diphosphate Reductase M2 Chain
    6 2iyh 41.9 0.8 274 275 80 Ribonucleoside-diphosphate Reductase M2 Subunit
    7 3hf1 41.8 1.2 282 286 96 Ribonucleoside-diphosphate Reductase Subunit M2
    8 2uw2 41.8 0.9 274 275 80 Ribonucleoside-diphosphate Reductase M2 Subunit
    9 2vux 38.5 1.3 271 272 94 Ribonucleoside-diphosphate Reductase Subunit M2 B
    10 1jk0 37.5 1.7 285 334 67 Ribonucleoside-diphosphate Reductase Small Chain

     

     

    A superposition of a few of these is shown below.

    MA16109D_1h0o_1xsm_3hf1.png.

    Color scheme: NP_056528.2(green), 1h0o (cyan), 1xsm (magenta), 3hf1 (yellow).

    Ligand Summary

    Reviews

    References

     

    No references found.

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