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The Open Protein Structure Annotation Network
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3s30

    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title Crystal structure of a Hypothetical glycoside hydrolase (BVU_0247) from Bacteroides vulgatus ATCC 8482 at 2.46 A resolution. To be published
    Site JCSG
    PDB Id 3s30 Target Id
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    Molecular Characteristics
    Source
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    Alias Ids
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    TPS27813,YP_001297591.1, 324101
    Molecular Weight
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    Da.
    Residues
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    Isoelectric Point
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    Sequence
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      BLAST   FFAS

    Structure Determination
    Method XRAY
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    Chains 2
    Resolution (Å)
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    Rfree
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    Matthews' coefficent 3.59 Rfactor 0.2325
    Waters
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    Solvent Content 65.78

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    Ligand Information
    Ligands
    Metals

    Jmol

     
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    Google Scholar output for 3s30
    1. HIV Protein Sequence Hotspots for Crosstalk with Host Hub Proteins
    M Sarmady, W Dampier, A Tozeren - PloS one, 2011 - dx.plos.org
     
    2. Sequence-and Interactome-Based Prediction of Viral Protein Hotspots Targeting Host Proteins: A Case Study for HIV Nef
    M Sarmady, W Dampier, A Tozeren - PloS one, 2011 - dx.plos.org
     

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    Protein Summary


    Target GS13522A (ID 393205) shares about 42.4% sequence identity with the C-t subdomain of a putative Glycoside hydrolase (pdb 3HBZ), solved also by the JCSG. The structure of this protein has a jelly-roll fold (Galactose-binding domain-like according to SCOP, see Topsan for 3HBZ). HHpred analysis against Pfam indicated that target GS13522A belongs to Glyco_hydro_44 - family of putative bacterial glycoside hydrolases (PF12891, prob 100.0, E-val 0). As expected, the structural analysis also shows similarities with the putative Glycoside hydrolase (3HBZ) - FATCAT/DALI top hit PUTATIVE GLYCOSIDE HYDROLASE (Pdb 3hbzA, Z-score 25.4, rmsd 1.8, P-value 1.61e-10).       

    Ligand Summary

    Reviews

    References

     

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