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3rh3

    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title Crystal structure of an Uncharacterized DUF3829-like protein (BT_1908) from BACTEROIDES THETAIOTAOMICRON VPI-5482 at 2.10 A resolution. To be published
    Site JCSG
    PDB Id 3rh3 Target Id
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    Molecular Characteristics
    Source
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    Alias Ids
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    TPS63449,NP_810821.1, 332558
    Molecular Weight
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    Da.
    Residues
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    Isoelectric Point
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    Sequence
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      BLAST   FFAS

    Structure Determination
    Method XRAY
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    Chains 2
    Resolution (Å)
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    Rfree
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    Matthews' coefficent 2.24 Rfactor 0.2121
    Waters
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    Solvent Content 45.17

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    Ligand Information
    Ligands
    Metals

    Jmol

     
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    Google Scholar output for 3rh3

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    Protein Summary

    Pfam Update: I have built this with jackhmmer this morning and the N-terminal half overlaps entirely with a DUF I built last year from 3iee:
    ID DUF3829
    AC PF12889
    DE Protein of unknown function (DUF3829)
    AU Coggill P
    SE JCSG_target_393163_3iee
    GA 21.30 21.30;
    TC 21.30 21.30;
    NC 21.10 21.00;
    BM hmmbuild --amino -o /dev/null HMM SEED
    SM hmmsearch -Z 11384036 -E 1000 --cpu 4 HMM pfamseq
    TP Family WK Domain_of_unknown_function This is a small family of proteins from several bacterial species, whose function is not known. It may, however, be related to the GvpL_GvpF family of proteins, Pfam:PF06386. That was a shorter protein, but there were only a handful of members here with the longer tail. This might be interesting, but I will close the ticket until the structure comes through.

     

     

    Target 386294 shows sequence and structural similarity with the protein 3iee (FFAS Score -94.600; Dali/FATCAT P-value 0.00e+00)

    3iee, that is functionally uncharacterized, is  a member of DUF3829 pfam family (PF12889). 

    Target 386294 is composed by all alpha domains (see image). The N-terminal domain shows a weak similarity to vinculin (Dali, 1rkc-A, Z-score 10.1) and the C-terminal to aspartate receptor ( Dali, 2asr-A  Z-score 9.9).

    Ligand Summary

    Reviews

    References

     

    No references found.

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    Files (1)

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    261.46 kB17:00, 24 Mar 2011marianaActions
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