The Open Protein Structure Annotation Network
PDB Keyword


    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title Crystal structure of a PTS dependent N-acetyl-galactosamine-IIB component (agaV, SPy_0631) from Streptococcus pyogenes at 1.65 A resolution. To be published
    Site JCSG
    PDB Id 3p3v Target Id 399539
    Molecular Characteristics
    Source Streptococcus pyogenes m1 gas
    Alias Ids TPS29740,NP_268878.1, _0035.002091_, 324900 Molecular Weight 17872.68 Da.
    Residues 162 Isoelectric Point 6.03
    Sequence mtqpniimtrvderlihgqgqlwvkflncntvivandavsedkiqqslmktvipssiairffsiqkvid iihkaspaqsifivvkdlqdakllveggvpiteinignihktddkvaitqfislgetdksairclahdh hvvfntkttpagnsasdvdildyi
      BLAST   FFAS

    Structure Determination
    Method XRAY Chains 2
    Resolution (Å) 1.65 Rfree 0.1939
    Matthews' coefficent 2.14 Rfactor 0.1584
    Waters 301 Solvent Content 42.53

    Ligand Information


    Google Scholar output for 3p3v

    Protein Summary

    This protein is annotated as a putative PTS dependent N-acetyl-galactosamine-IIB component (EC:2.7.1.-, putatively EC: from Streptococcus pyogenes belonging to PFAM:PF03830

    It is present as a monomer in the crystal structure and analytical size-exclusion chromatography supports a monomer as the significant oligomeric state in solution.


    The structures of several other similar proteins are available ranging from 25-33% sequence identity with PDB ids PDB:1nrz, PDB:3eye, PDB:1ble and PDB:2jzh.

    There are some differences between the monomers in the ASU in addition to differences in the loop regions:
    like the backbone flip near residue 18, e.g. O from residue 18 interacts with Arg-10 in the B-chain while in the A chain O from residue 18 interacts with backbone N from residue 21.

    Ligand Summary




    No references found.

    Tag page
    • No tags

    Files (1)

    FileSizeDateAttached by 
    No description
    345.39 kB23:20, 30 Sep 2010debanuActions
    You must login to post a comment.
    All content on this site is licensed under a Creative Commons Attribution 3.0 License
    Powered by MindTouch