The Open Protein Structure Annotation Network
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    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title Crystal structure of a putative 2OG-Fe(II) oxygenase family protein (CC_0200) from CAULOBACTER CRESCENTUS at 1.44 A resolution. To be published
    Site JCSG
    PDB Id 3oox Target Id 398027
    Molecular Characteristics
    Source Caulobacter crescentus cb15
    Alias Ids TPS29626,NP_419019.1, _0052.002434_, _0076.002207_, 327951 Molecular Weight 34692.46 Da.
    Residues 311 Isoelectric Point 5.62
    Sequence mstsaidpvsfslyakdftrfaqelgasferygfavlsdydldqaridaavdsakaffalpvetkkqya gvkggargyipfgvetakgadhydlkefwhmgrdlppghrfrahmadnvwpaeipafkhdvswlynsld gmggkvleaiatylklerdffkptvqdgnsvlrllhyppipkdatgvragahgdintitlllgaeeggl evldrdgqwlpinpppgclvinigdmlerltnnvlpstvhrvvnppperrgvprystpfflhfasdyei ktlqncvtaenpdrypesitadeflqqrlreikla
      BLAST   FFAS

    Structure Determination
    Method XRAY Chains 2
    Resolution (Å) 1.44 Rfree 0.1969
    Matthews' coefficent 2.37 Rfactor 0.1690
    Waters 849 Solvent Content 48.10

    Ligand Information


    Google Scholar output for 3oox
    1. Blind prediction of quaternary structures of homo-oligomeric proteins from amino acid sequences based on templates
    M Morita, M Kakuta, K Shimizu, S Nakamura - 2012 - hoajonline.com

    Protein Summary

     Pfam Update: this protein is now in family: 2OG-FeII_Oxy (PF03171), which has many structures.


    Gene  NP_419019.1 from bacteria Caulobacter crescentus  ecodes the corresponding protein with 311 residues. The structure is characterized against MAD data with the resolution up to 1.70 Ang.  Sequence alignment indicates that this protein could be 2OG-Fe(II) oxygenase. Dali search and SSM alignment also suggest that this protein should be a structural homolog to 1-aminocyclopropane-1-carboxylic acid oxidase--the ethylene-forming enzyme, isopenicillin N-synthase and deacetoxycephalosporin C-synthase.  The biolomolecule of protein NP_419019.1 should be a monomer according the interface interaction (PISA).


    Figure 1. Protein NP_419019.1 monomer.

    Ligand Summary




    No references found.

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    315.58 kB18:04, 14 Jun 2010kevinjinActions
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