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3jxo

    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title Crystal Structure of an Octomeric Two-Subunit TrkA K+ Channel Ring Gating Assembly, TM1088A:TM1088B, from Thermotoga maritima. To be Published
    Site JCSG
    PDB Id 3jxo Target Id
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    Molecular Characteristics
    Source
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    Alias Ids
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    TPS30798,TM1088B
    Molecular Weight
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    Da.
    Residues
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    Isoelectric Point
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    Sequence
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      BLAST   FFAS

    Structure Determination
    Method XRAY
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    Chains 2
    Resolution (Å)
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    Rfree
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    Matthews' coefficent 2.59 Rfactor 0.15780
    Waters
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    Solvent Content 52.53

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    Ligand Information
    Ligands
    Metals

    Jmol

     
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    Google Scholar output for 3jxo

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    Protein Summary

    The TM1088 gene from Thermotoga maritima encodes the NP_228894 protein containing in its C-terminal part (148-216) a potassium uptake (TrkA-C) domain (PF02080, COG0569). Genome context analysis indicates a likely (score 0.98) functional linkage of TM1088 with the TRK system potassium uptake protein TrkH (TM1089).

    3jxo adopts a new fold termed TrkA C-terminal domain-like. 3jxo shows significant structural similarity to other TrkA C-terminal domains  like 1VCT (Z=9.6), 1lnq (Z=9.8), and 2bko (Z=9.9).

    For more information on the structure and function of this family, see related publications [Ref][Ref].

    Ligand Summary

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