The Open Protein Structure Annotation Network
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    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary
    3. 3. References

    Title Crystal structure of putative metal-dependent hydrolase (YP_805737.1) from Lactobacillus casei ATCC 334 at 1.40 A resolution. To be published
    Site JCSG
    PDB Id 2qpx Target Id 375624
    Molecular Characteristics
    Source Lactobacillus casei atcc 334
    Alias Ids TPS1658,LCAS_20SEP02_SCAFFOLD4_REVISED_GENE2707, 103701 Molecular Weight 42568.20 Da.
    Residues 375 Isoelectric Point 5.65
    Sequence lddlsefvdqvplldhhchflidgkvpnrddrlaqvsteadkdypladtknrlayhgflalakefalda nnplaamndpgyatynhrifghfhfkellidtgfvpddpildldqtaelvgipvkaiyrlethaedfml ehdnfaawwqafsndvkqakahgfvgfksiaayrvglhlepvnvieaaagfdtwkhsgekrltskplid ymlyhvapfiiaqdmplqfhvgygdadtdmylgnpllmrdylkaftkkglkvvllhcypyhreagylas vfpnlyfdislldnlgpsgasrvfneavelapytrilfasdastypemyglaarqfkqalvahfnqlpf vdlaqkkawinaicwqtsaklyhqerelrv
      BLAST   FFAS

    Structure Determination
    Method XRAY Chains 1
    Resolution (Å) 1.40 Rfree 0.162
    Matthews' coefficent 2.78 Rfactor 0.134
    Waters 494 Solvent Content 55.71

    Ligand Information


    Google Scholar output for 2qpx
    1. Decision-making in structure solution using Bayesian estimates of map quality: the PHENIX AutoSol wizard
    TC Terwilliger, PD Adams, RJ Read - Section D: Biological , 2009 - scripts.iucr.org
    2. Reversible post-translational carboxylation modulates the enzymatic activity of N-acetyl-L-ornithine transcarbamylase
    Y Li, X Yu, J Ho, D Fushman, N Allewell - Biochemistry, 2010 - ACS Publications

    Protein Summary

    The LSEI_0440 gene (PF04909, cl00281) from Lactobacillus casei ATCC 334 encodes for a protein in a huge metallo-dependent hydrolase family (PF01979). Although current CATH and SCOP do not classify this protein structure, structural similarity to 2pnk allows to insert this TIM barrel structure to the metallo-dependent hydrolases in SCOP. Other similar structures determined by PSI are 2qee and 1j5s.

    Ligand Summary





    No references found.

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