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The Open Protein Structure Annotation Network
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1vll

    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary
    3. 3. References

    Title Crystal structure of alanine dehydrogenase (AF1665) from Archaeoglobus fulgidus at 2.80 A resolution. To be published
    Site JCSG
    PDB Id 1vll Target Id
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    Molecular Characteristics
    Source
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    Alias Ids
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    TPS1328,2648890
    Molecular Weight
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    Da.
    Residues
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    Isoelectric Point
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    Sequence
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      BLAST   FFAS

    Structure Determination
    Method XRAY
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    Chains 2
    Resolution (Å)
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    Rfree
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    Matthews' coefficent 2.38 Rfactor 0.21742
    Waters
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    Solvent Content 48.22

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    Ligand Information
    Ligands
    Metals

    Jmol

     
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    Google Scholar output for 1vll
    1. His-tag impact on structure
    M Carson, DH Johnson, H McDonald - Section D: Biological , 2007 - scripts.iucr.org
     
    2. Protein structure prediction based on the sliced lattice model
    CC Wang, CB Yang, HY Ann - 2008 Conference on , 2005 - etd.lib.nsysu.edu.tw
     
    3. Prediction of Protein Backbone Based on the Sliced Lattice Model
    CC Wang, CB Yang, HY Ann, HY Chang - 2008 - csie.npu.edu.tw
     
    4. The Buccaneer software for automated model building. 1. Tracing protein chains
    K Cowtan - Acta Crystallographica Section D: Biological , 2006 - scripts.iucr.org
     

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    Protein Summary

    The gene 2648890 from Archaeoglobus fulgidus encodes the enzyme alanine dehydrogenase EC:1.4.1.1 COG0686, a member of ornithine cyclodeaminase family PF02423.  The enzyme belongs to the class of alpha and beta (a+b) proteins and reveals NAD(P)-binding Rossmann-fold domain fold type SCOP51734. The enzyme catalyzes the follwing reaction: L-alanine + H(2)O + NAD(+) <=> pyruvate + NH(3) + NADH.  The enzyme participates in taurine and hypotaurine metabolism and reductive carboxylate cycle (CO2 fixation).  The structure of the enzyme homologue with bound NAD from Archaeoglobus has been solved 1OMO.

    Ligand Summary



    References

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