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1u65

    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title The crystal structure of the complex of the anticancer prodrug 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin (CPT-11) with Torpedo californica acetylcholinesterase provides a molecular explanation for its cholinergic action. Mol.Pharmacol. 67 1874-1881 2005
    Site ISPC
    PDB Id 1u65 Target Id
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    Molecular Characteristics
    Source
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    Alias Ids
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    TPS11915,P04058
    Molecular Weight
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    Da.
    Residues
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    Isoelectric Point
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    Sequence
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      BLAST   FFAS

    Structure Determination
    Method XRAY
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    Chains 1
    Resolution (Å)
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    Rfree
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    Matthews' coefficent 3.17 Rfactor 0.187
    Waters
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    Solvent Content 61.20

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    Ligand Information
    Ligands NDG-FUL (2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE) x 1;NAG (BETA-L-FUCOSE) x 2;NAG-FUC (N-ACETYL-D-GLUCOSAMINE) x 1;NAG-MAN (N-ACETYL-D-GLUCOSAMINE) x 1;CP0 (ALPHA-L-FUCOSE) x 1
    Metals IOD (IODIDE) x 1

    Jmol

     
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    Google Scholar output for 1u65

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    Protein Summary


    Ligand Summary

    Reviews

    References

     

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