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PF13660

    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

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    Resources
    Pfam ID: DUF4147 PDB: 1x3l_A
    Solved by: RSGI Priority Score: 4.6
    Member of this family is in PDB.
    Co-occurence with annotated domain(s) (no restrictions on number of architectures).
    HMMER:
      # sequence matches: 598 # architectures: 5 # taxonomy ids:410
    FFAS:
      Top FFAS hit in PDB: "2b8nA, glycerate kinase, putative" No significant hits in Pfam.
    GRDB:
      Top significant hit (PDB90): "2b8nA, transferase ; crystal structure of glycerate kinase (ec 2.7.1.31) (tm1585) from thermotoga maritima at 2.70 a resolution "
    CATH: CATH Domain E-value CATH Node
      1x3lA02 2.00E-77 3.40.50.10180
    FUNFAM (eval=0 ): Putative hydroxypyruvate reductase -like
    PUBSERVER:
      Publications(s) found: 367
      Publications(s) meeting filtering criteria: 12
    GeneSilico Metaserver: (Login and password: Jamboree)
    PDBBLAST: PDB: 1x3l_A SCOP: predicted c.118.1.1 ECC: 2.7.1.31
    FFAS: PDB: 1x3l_A SCOP: predicted c.118.1.1 ECC: 2.7.1.31
    MGENTHREADER: PDB: 1x3l_A SCOP: predicted c.118.1.1 ECC: 2.7.1.31
    PRC: PDB: 2b8n_A SCOP: predicted c.118.1.1 ECC: 2.7.1.31
    SPARKS: PDB: 1o0u_A
    BLASTP: PDB: 1x3l_A SCOP: predicted c.118.1.1 ECC: 2.7.1.31
    HHBLITS: PDB: 1x3l_A SCOP: predicted c.118.1.1 ECC: 2.7.1.31
    COMPASS: PDB: 1x3l_A SCOP: predicted c.118.1.1 ECC: 2.7.1.31
    COMA: PDB: 1x3l_A SCOP: predicted c.118.1.1 ECC: 2.7.1.31
    CSBLAST: PDB: 1x3l_A SCOP: predicted c.118.1.1 ECC: 2.7.1.31
    HHSEARCH: PDB: 1x3l_A SCOP: predicted c.118.1.1 ECC: 2.7.1.31

    Topsan Members

    Tag pages as 'PF13660' to appear in this list.

    No TOPSAN member(s) found.

    Summary

    This is a Rossmann fold domain appears in several cofactor-dependent reductases. Its Rossmann fold supports a reductase function. However a  version from Thermotoga has been annotated as a glycerate kinase. Probably has to remain a DUF.

    Reviews

    References

     

    No references found.

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