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PF13204

    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

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    Resources
    Pfam ID: DUF4038 PDB: 3kzs_A
    Solved by: JCSG Priority Score: 3.6
    Member of this family is in PDB.
    Member of this clan is in PDB.
    Co-occurence with annotated domain(s) (no restrictions on number of architectures).
    HMMER:
      # sequence matches: 219 # architectures: 9 # taxonomy ids:118
    FFAS:
      Top FFAS hit in PDB: "3kzsA, glycosyl hydrolase family 5" Top FFAS hit in Pfam: "PF00150, Cellulase (glycosyl hydrolase family 5) "
    GRDB:
      Top significant hit (PDB90): "3kzsA, hydrolase ; crystal structure of glycosyl hydrolase family 5 (np_809925.1) from bacteroides thetaiotaomicron vpi-5482 at 2.10 a resolution "
      Top significant hit (PFAM25U): "PF00150, Cellulase (glycosyl hydrolase family 5)"
    CATH: CATH Domain E-value CATH Node
      3cmgA03 0.002 3.20.20.80
      3gm8A03 0.0013
    FUNFAM (eval=0.0018 ): Major extracellular endoglucanase -like
    PUBSERVER:
      Publications(s) found: 95
      Publications(s) meeting filtering criteria: 4
    GeneSilico Metaserver: (Login and password: Jamboree)
    FFAS: PDB: 1qno_A SCOP: c.1.8.3 ECC: 3.2.1.78
    PHYRE: PDB: 1qnr_A SCOP: c.1.8.3 ECC: 3.2.1.78
    MGENTHREADER: PDB: 2pc8_A SCOP: predicted c.1.8.3 ECC: 3.2.1.58
    PRC: PDB: 1ceo_A SCOP: c.1.8.3 ECC: 3.2.1.4
    HHBLITS: PDB: 3kzs_A
    COMPASS: PDB: 1qno_A SCOP: c.1.8.3 ECC: 3.2.1.78
    COMA: PDB: 1uuq_A SCOP: c.1.8.3 ECC: predicted 3.2.-.-
    HHSEARCH: PDB: 3kzs_A

    Topsan Members

    Tag pages as 'PF13204' to appear in this list.

    No TOPSAN member(s) found.

    Summary

    Belongs to glycosyl hydrolase clan (CL0058). Can be found as a fusion with either the collagen-binding (PF12904) domain or the PTS-IIA component (PF00358), confirming its implication in carbohydrate utilization. Often co-localized on the chromosome with a sugar kinase and an isomerase of unknown specificity, as well as a transketolase. In Thermotoga maritima this gene (TM0950) is located in the ribose utilization operon, which is upregulated on ribose. Can be involved in hydrolysis of unknown pentose-containing saccharide. 

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