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    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

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    Pfam ID: DUF2027 PDB: 2huh_A
    Solved by: JCSG Priority Score: 2.6
    Member of this family is in PDB.
    Co-occurence with annotated domain(s) (no restrictions on number of architectures).
      # sequence matches: 85 # architectures: 2 # taxonomy ids:70
      Top FFAS hit in PDB: "2huhA, Putative DNA mismatch repair protein" No significant hits in Pfam.
      Top significant hit (PDB90): "2huhA, structural genomics, unknown function ; crystal structure of putative dna mismatch repair protein (np_811092.1) from bacteroides thetaiotaomicron vpi-5482 at 1.54 a resolution "
    CATH: CATH Domain E-value CATH Node
      2huhA01 6.90E-53
      Publications(s) found: 15
      Publications(s) meeting filtering criteria: 0
    GeneSilico Metaserver: (Login and password: Jamboree)
    PDBBLAST: PDB: 2huh_A
    FFAS: PDB: 2huh_A
    BLASTP: PDB: 2huh_A
    HHBLITS: PDB: 2huh_A
    COMPASS: PDB: 2huh_A
    COMA: PDB: 2huh_A
    CSBLAST: PDB: 2huh_A
    HHSEARCH: PDB: 2huh_A

    Topsan Members

    Tag pages as 'PF09640' to appear in this list.

    Name Annotation Author(s)
    The protein product of the BT_2179 (NP_811092) gene from Bacteroides thetaiotaomicron VPI-5482 is a three domain protein, with a central domain (91-252) belonging to the DUF2027 group (PF09640) and a ... pascual (9 edits)
    tinaAdmin (2 edits)
    adam (2 edits)


    Pfam family PFAM:PF09640 {Domain of unknown function (DUF2027) } with 7 members in NR database and additional 2 members in the metagenomic datasets is represented in Bacteria. The first structural representative solved (PDB Id: TOPSAN:2huh) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1vjja3 classified as Immunoglobulin-like beta-sandwich fold. (Note: additional/lacking secondary structure elements). Based on marginal prediction from FFAS confirmed by structural similarity one can argue that this family is remotely homologous to previously known structures from 'd1vjja3' this fold.




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