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PF09167

    Table of contents
    1. 1. Topsan Members
    2. 2. Summary
    3. 3. References

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    Resources
    Pfam ID: DUF1942 PDB: 1lmi_A
    Solved by: TBSGC Priority Score: 1.6
    Member of this family is in PDB.
    HMMER:
      # sequence matches: 32 # architectures: 1 # taxonomy ids:12
    FFAS:
      Top FFAS hit in PDB: "1lmiA, Immunogenic protein MPT63/MPB63" No significant hits in Pfam.
    GRDB:
      Top significant hit (PDB90): "1lmiA, immune system ; 1.5 angstrom resolution crystal structure of a secreted protein from mycobacterium tuberculosis-mpt63 "
      Top significant hit (PFAM25U): "PF11611, Domain of unknown function (DUF4352)"
    CATH: CATH Domain E-value CATH Node
      3cfuB00 0.0014 2.60.40.1240
    FUNFAM (eval=0 ): Immunogenic protein MPT63 -like
    PUBSERVER:
      Publications(s) found: 36
      Publications(s) meeting filtering criteria: 5
    GeneSilico Metaserver: (Login and password: Jamboree)
    PDBBLAST: PDB: 1lmi_A SCOP: b.1.19.1
    FFAS: PDB: 1lmi_A SCOP: b.1.19.1
    PRC: PDB: 1lmi_A SCOP: b.1.19.1
    SPARKS: PDB: 1lmi_A SCOP: b.1.19.1
    BLASTP: PDB: 1lmi_A SCOP: b.1.19.1
    HHBLITS: PDB: 1lmi_A SCOP: b.1.19.1
    COMPASS: PDB: 1lmi_A SCOP: b.1.19.1
    CSBLAST: PDB: 1lmi_A SCOP: b.1.19.1
    HHSEARCH: PDB: 1lmi_A SCOP: b.1.19.1

    Topsan Members

    Tag pages as 'PF09167' to appear in this list.

    Name Annotation Author(s)
    1lmi

    Summary

    Pfam family
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    {Domain of unknown function (DUF1942)} with 41 members in NR database. The first structural representative solved (PDB Id:
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    ) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain
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    classified as Immunoglobulin-like beta-sandwich fold. However, no sequence similarity to this fold has been detected. Based on sequence and structure analysis/ original paper one can hypothesize that this family is structural similarity suggests that MPT63 could be involved in cell-host interactions to facilitate endocytosis/phagocytosis

    Reviews

    References

     

    No references found.

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