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    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

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    Pfam ID: DUF1887 PDB: 1xmx_A
    Solved by: MCSG Priority Score: 2.6
    Member of this family is in PDB.
    Member of this clan is in PDB.
      # sequence matches: 158 # architectures: 10 # taxonomy ids:99
      Top FFAS hit in PDB: "1xmxA, hypothetical protein VC1899" Top FFAS hit in Pfam: "PF09670, CRISPR-associated protein (Cas_Cas02710) "
      Top significant hit (PDB90): "1xmxA, structural genomics, unknown function ; crystal structure of protein vc1899 from vibrio cholerae "
      Top significant hit (PFAM25U): "PF09670, CRISPR-associated protein (Cas_Cas02710)"
    CATH: CATH Domain E-value CATH Node
      1xmxA01 7.00E-34
      1y88A01 5.50E-06 3.40.1350.10
      1xmxA03 1.70E-19
      Publications(s) found: 73
      Publications(s) meeting filtering criteria: 1
    GeneSilico Metaserver: (Login and password: Jamboree)
    PDBBLAST: PDB: 1xmx_A SCOP: c.52.1.26
    FFAS: PDB: 1xmx_A SCOP: c.52.1.26
    MGENTHREADER: PDB: 1xmx_A SCOP: c.52.1.26
    PRC: PDB: 1xmx_A SCOP: c.52.1.26
    SPARKS: PDB: 1xmx_A SCOP: c.52.1.26
    BLASTP: PDB: 1xmx_A SCOP: c.52.1.26
    HHBLITS: PDB: 1xmx_A SCOP: c.52.1.26
    COMPASS: PDB: 1xmx_A SCOP: c.52.1.26
    COMA: PDB: 1xmx_A SCOP: c.52.1.26
    CSBLAST: PDB: 1xmx_A SCOP: c.52.1.26
    HHSEARCH: PDB: 1xmx_A SCOP: c.52.1.26

    Topsan Members

    Tag pages as 'PF09002' to appear in this list.

    Name Annotation Author(s)


    Pfam family PFAM:PF09002 {Domain of unknown function (DUF1887) } with 23 members in NR database and additional 10 members in the metagenomic datasets is represented in Archaea, and Bacteria. The first structural representative solved (PDB Id: TOPSAN:1xmx) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1cfra_ classified as Restriction endonuclease-like fold. Profile-profile methods confirm remote homology between this family and superfamily of Restriction endonuclease-like; fold of the same name. Based on remote homology confirmed by the structure one can hypothesize that this family is probably involved in processing of nucleic acids




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