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PDB Keyword
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PF08969

    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

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    Resources
    Pfam ID: DUF1873 PDB: 2a9u_A
    Solved by: SGC Priority Score: 3.6
    Member of this family is in PDB.
    Co-occurence with annotated domain(s) (no restrictions on number of architectures).
    HMMER:
      # sequence matches: 63 # architectures: 8 # taxonomy ids:40
    FFAS:
      Top FFAS hit in PDB: "2a9uA, Ubiquitin carboxyl-terminal hydrolase 8" Top FFAS hit in Pfam: "PF04212, MIT (microtubule interacting and transport) domain "
    GRDB:
      Top significant hit (PDB90): "2a9uA, hydrolase ; structure of the n-terminal domain of human ubiquitin carboxyl-terminal hydrolase 8 (usp8) "
    CATH: CATH Domain E-value CATH Node
      2a9uB00 2.50E-30
    PUBSERVER:
      Publications(s) found: 154
      Publications(s) meeting filtering criteria: 58
    GeneSilico Metaserver: (Login and password: Jamboree)
    PDBBLAST: PDB: 2a9u_A SCOP: predicted a.118.23.1 ECC: 3.1.2.15
    FFAS: PDB: 2a9u_A SCOP: predicted a.118.23.1 ECC: 3.1.2.15
    MGENTHREADER: PDB: 2a9u_A SCOP: predicted a.118.23.1 ECC: 3.1.2.15
    PRC: PDB: 2a9u_A SCOP: predicted a.118.23.1 ECC: 3.1.2.15
    BLASTP: PDB: 2a9u_A SCOP: predicted a.118.23.1 ECC: 3.1.2.15
    HHBLITS: PDB: 2a9u_A SCOP: predicted a.118.23.1 ECC: 3.1.2.15
    COMPASS: PDB: 2a9u_A SCOP: predicted a.118.23.1 ECC: 3.1.2.15
    CSBLAST: PDB: 2a9u_A SCOP: predicted a.118.23.1 ECC: 3.1.2.15
    HHSEARCH: PDB: 2a9u_A SCOP: predicted a.118.23.1 ECC: 3.1.2.15

    Topsan Members

    Tag pages as 'PF08969' to appear in this list.

    No TOPSAN member(s) found.

    Summary

    This domain is found at the N-terminus of USP8 proteins. Its structure shows it adopts a five helical bundle that forms a dimer. To be renamed in Pfam as USP8_N

    Reviews

    References

     

    No references found.

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