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The Open Protein Structure Annotation Network
PDB Keyword
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PF08939

    Table of contents
    1. 1. Topsan Members
    2. 2. Summary
    3. 3. References

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    Resources
    Pfam ID: DUF1917 PDB: 1ztp_A
    Solved by: CESG Priority Score: 2.6
    Member of this family is in PDB.
    HMMER:
      # sequence matches: 79 # architectures: 5 # taxonomy ids:58
    FFAS:
      Top FFAS hit in PDB: "1ztpA, Basophilic leukemia expressed protein BLES03" Top FFAS hit in Pfam: "PF01652, Eukaryotic initiation factor 4E "
    GRDB:
      Top significant hit (PDB90): "1ztpA, structural genomics, unknown function ; x-ray structure of gene product from homo sapiens hs.433573 "
      Top significant hit (PFAM25U): "PF01652, Eukaryotic initiation factor 4E"
    CATH: CATH Domain E-value CATH Node
      1ztpA01 4.90E-55 3.30.760.10
    PUBSERVER:
      Publications(s) found: 58
      Publications(s) meeting filtering criteria: 1
    GeneSilico Metaserver: (Login and password: Jamboree)
    PDBBLAST: PDB: 2q4k_A SCOP: predicted d.86.1.2
    FFAS: PDB: 1ztp_A SCOP: predicted d.86.1.2
    PRC: PDB: 1ztp_A SCOP: predicted d.86.1.2
    BLASTP: PDB: 2q4k_A SCOP: predicted d.86.1.2
    HHBLITS: PDB: 1ztp_A SCOP: predicted d.86.1.2
    COMPASS: PDB: 1ztp_A SCOP: predicted d.86.1.2
    CSBLAST: PDB: 2q4k_A SCOP: predicted d.86.1.2
    HHSEARCH: PDB: 1ztp_A SCOP: predicted d.86.1.2

    Topsan Members

    Tag pages as 'PF08939' to appear in this list.

    Name Annotation Author(s)
    1ztp

    Summary

    Pfam family PFAM:PF08939 {Domain of unknown function (DUF1917) } with 35 members in NR database and additional 1 members in the metagenomic datasets is represented in Archaea, Bacteria, and Eukaryota. The first structural representative solved (PDB Id: TOPSAN:1ztp) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1l8ba_ classified as Eif4e-like fold. Profile-profile methods confirm remote homology between this family and superfamily of eIF4e-like; fold of the same name. Based on sequence and structure analysis/ original paper one can hypothesize that this family is may be involved in a biochemical process that requires recognition of nucleic acids.

    Reviews

    References

     

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