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PDB Keyword
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PF08926

    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

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    Resources
    Pfam ID: DUF1908 PDB: 1v9v_A
    Solved by: RSGI Priority Score: 3.6
    Member of this family is in PDB.
    Co-occurence with annotated domain(s) (no restrictions on number of architectures).
    HMMER:
      # sequence matches: 145 # architectures: 10 # taxonomy ids:49
    FFAS:
      Top FFAS hit in PDB: "1v9vA, KIAA0561 protein" No significant hits in Pfam.
    GRDB:
      Top significant hit (PDB90): "1v9vA, structural genomics, unknown function ; solution structure of putative domain of human kiaa0561 protein "
      Top significant hit (PFAM25U): "PF11539, Protein of unknown function (DUF3228)"
    CATH: CATH Domain E-value CATH Node
      1v9vA01 1.10E-25 1.20.1480.20
    FUNFAM (eval=0 ): LD01372p -like
    PUBSERVER:
      Publications(s) found: 103
      Publications(s) meeting filtering criteria: 20
    GeneSilico Metaserver: (Login and password: Jamboree)
    FFAS: PDB: 1v9v_A SCOP: predicted a.29.10.1
    PHYRE: PDB: 1v9v_A SCOP: a.29.10.1
    MGENTHREADER: PDB: 1v9v_A SCOP: predicted a.29.10.1
    PRC: PDB: 1v9v_A SCOP: predicted a.29.10.1
    SPARKS: PDB: 1v9v_A SCOP: predicted a.29.10.1
    HHBLITS: PDB: 1v9v_A SCOP: predicted a.29.10.1
    COMPASS: PDB: 1v9v_A SCOP: predicted a.29.10.1
    COMA: PDB: 1v9v_A SCOP: predicted a.29.10.1
    HHSEARCH: PDB: 1v9v_A SCOP: predicted a.29.10.1

    Topsan Members

    Tag pages as 'PF08926' to appear in this list.

    No TOPSAN member(s) found.

    Summary

    DUF1908 has been classified as the PF08926 Pfam family. The solution NMR structure of a member of this Pfam has been determined and is represented by PDB ID 1v9v, a putative domain of the human KIAA0561 protein. An INTERPRO search shows that members of this target are annotated as being a single domain of microtuble-associated Ser/Thr protein kinases SCOP family. Members of this SCOP family show a bromodomain-like fold, suggesting that members of this DUF recognize acetylated lysines, and that members of this DUF are involved in protein-chromatin interactions. 

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