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PF08924

    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

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    Resources
    Pfam ID: DUF1906 PDB: 1sfs_A
    Solved by: MCSG Priority Score: 2.6
    Member of this family is in PDB.
    Co-occurence with annotated domain(s) (no restrictions on number of architectures).
    HMMER:
      # sequence matches: 257 # architectures: 16 # taxonomy ids:131
    FFAS:
      Top FFAS hit in PDB: "1sfsA, Hypothetical protein" No significant hits in Pfam.
    GRDB:
      Top significant hit (PDB90): "1sfsA, structural genomics, unknown function ; 1.07 a crystal structure of an uncharacterized b. stearothermophilus protein "
      Top significant hit (PFAM25U): "PF01183, Glycosyl hydrolases family 25"
    CATH: CATH Domain E-value CATH Node
      1sfsA00 2.40E-35 3.20.20.80
      3ju2A00 0.0015
      1i60A00 0.0006 3.20.20.150
    PUBSERVER:
      Publications(s) found: 143
      Publications(s) meeting filtering criteria: 3
    GeneSilico Metaserver: (Login and password: Jamboree)
    FFAS: PDB: 1sfs_A SCOP: c.1.8.8
    PHYRE: PDB: 1sfs_A SCOP: c.1.8.8
    PRC: PDB: 1sfs_A SCOP: c.1.8.8
    HHBLITS: PDB: 2x8r_A ECC: 3.2.1.17
    COMPASS: PDB: 1sfs_A SCOP: c.1.8.8
    HHSEARCH: PDB: 1sfs_A SCOP: c.1.8.8

    Topsan Members

    Tag pages as 'PF08924' to appear in this list.

    Name Annotation Author(s)
    1sfs

    Summary

    Pfam family PFAM:PF08924 {Domain of unknown function (DUF1906) } with 64 members in NR database and additional 5 members in the metagenomic datasets is represented in Bacteria. The first structural representative solved (PDB Id: TOPSAN:1sfs) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1jfxa_ classified as TIM beta/alpha-barrel fold. Based on marginal prediction from FFAS confirmed by structural similarity one can argue that this family is remotely homologous to previously known structures from 'd1jfxa_' this fold.

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