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The Open Protein Structure Annotation Network
PDB Keyword
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PF08848

    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

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    Resources
    Pfam ID: DUF1818 PDB: 2it9_A
    Solved by: JCSG Priority Score: 1.6
    Member of this family is in PDB.
    HMMER:
      # sequence matches: 59 # architectures: 1 # taxonomy ids:30
    FFAS:
      Top FFAS hit in PDB: "2it9A, Hypothetical protein" No significant hits in Pfam.
    GRDB:
      Top significant hit (PDB90): "2it9A, structural genomics/unknown function ; crystal structure of hypothetical protein (yp_292156.1) from prochlorococcus sp. natl2a at 1.80 a resolution "
    CATH: CATH Domain E-value CATH Node
      2nvnA00 1.70E-44 2.30.31.10
    PUBSERVER:
      Publications(s) found: 29
      Publications(s) meeting filtering criteria: 0
    GeneSilico Metaserver: (Login and password: Jamboree)
    PDBBLAST: PDB: 2nvn_A SCOP: predicted d.18.1.3
    FFAS: PDB: 2it9_A SCOP: d.18.1.3
    MGENTHREADER: PDB: 2nvn_A SCOP: predicted d.18.1.3
    PRC: PDB: 2nvn_A SCOP: predicted d.18.1.3
    BLASTP: PDB: 2nvn_A SCOP: predicted d.18.1.3
    HHBLITS: PDB: 2nvn_A SCOP: predicted d.18.1.3
    COMPASS: PDB: 2nvn_A SCOP: predicted d.18.1.3
    COMA: PDB: 2it9_A SCOP: d.18.1.3
    CSBLAST: PDB: 2nvn_A SCOP: predicted d.18.1.3
    HHSEARCH: PDB: 2nvn_A SCOP: predicted d.18.1.3

    Topsan Members

    Tag pages as 'PF08848' to appear in this list.

    Name Annotation Author(s)
    2it9
    YP_292156 from Prochlorococcus sp. NATL2A and its homologs are bacterial proteins with unknown function from a PFAM family PF08848 (DUF1818) with a ssDNA-binding transcriptional regulator domain fold,...

    Summary

    Pfam family
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    {Domain of unknown function (DUF1818) } with 145 members in NR database and additional 118 members in the metagenomic datasets is represented in Bacteria. The first structural representative solved (PDB Id:
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    ) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain
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    classified as Ssdna-binding transcriptional regulator domain fold. However, no sequence similarity to this fold has been detected. Based on fold one can hypothesize that this family is possibly transcriptional regulator

    Reviews

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