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The Open Protein Structure Annotation Network
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PF08682

    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

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    Resources
    Pfam ID: DUF1780 PDB: 1y0k_A
    Solved by: MCSG Priority Score: 1.6
    Member of this family is in PDB.
    HMMER:
      # sequence matches: 28 # architectures: 1 # taxonomy ids:9
    FFAS:
      Top FFAS hit in PDB: "1y0kA, hypothetical protein PA4535" No significant hits in Pfam.
    GRDB:
      Top significant hit (PDB90): "1y0kA, structural genomics, unknown function ; hypothetical protein pa4535 from pseudomonas aeruginosa strain pao1 "
    CATH: CATH Domain E-value CATH Node
      1y0kA00 3.80E-100 3.40.1540.10
    PUBSERVER:
      Publications(s) found: 34
      Publications(s) meeting filtering criteria: 0
    GeneSilico Metaserver: (Login and password: Jamboree)
    PDBBLAST: PDB: 1y0k_A SCOP: predicted c.52.1.31
    FFAS: PDB: 1y0k_A SCOP: predicted c.52.1.31
    MGENTHREADER: PDB: 1y0k_A SCOP: predicted c.52.1.31
    PRC: PDB: 1y0k_A SCOP: predicted c.52.1.31
    SPARKS: PDB: 1y0k_A SCOP: predicted c.52.1.31
    BLASTP: PDB: 1y0k_A SCOP: predicted c.52.1.31
    HHBLITS: PDB: 1y0k_A SCOP: predicted c.52.1.31
    COMPASS: PDB: 1y0k_A SCOP: predicted c.52.1.31
    CSBLAST: PDB: 1y0k_A SCOP: predicted c.52.1.31
    HHSEARCH: PDB: 1y0k_A SCOP: predicted c.52.1.31

    Topsan Members

    Tag pages as 'PF08682' to appear in this list.

    Name Annotation Author(s)
    1y0k

    Summary

    Pfam family PFAM:PF08682 {Protein of unknown function (DUF1780) } with 19 members in NR database and additional 4 members in the metagenomic datasets is represented in Bacteria. The first structural representative solved (PDB Id: TOPSAN:1y0k) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d2foka4 classified as Restriction endonuclease-like fold. Based on marginal prediction from FFAS confirmed by structural similarity (possible only when domain boundaries are defined based on solved structure) one can argue that this family is remotely homologous to previously known structures from 'd2foka4' this fold. Based on fold and evidence of homology one can hypothesize that this family is probably involved in processing of nucleic acids

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