The Open Protein Structure Annotation Network
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    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

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    Pfam ID: DUF1273 PDB: 2nx2_A
    Solved by: NYSGXRC Priority Score: 2.6
    Member of this family is in PDB.
    Member of this clan is in PDB.
      # sequence matches: 452 # architectures: 4 # taxonomy ids:201
      Top FFAS hit in PDB: "2nx2A, Hypothetical protein ypsA" Top FFAS hit in Pfam: "PF12694, Putative molybdenum carrier "
      Top significant hit (PDB90): "2nx2A, structural genomics, unknown function ; crystal structure of hypothetical protein ypsa from bacillus subtilis. "
      Top significant hit (PFAM25U): "PF02481, DNA recombination-mediator protein A"
    CATH: CATH Domain E-value CATH Node
      2nx2A00 8.90E-66
      Publications(s) found: 264
      Publications(s) meeting filtering criteria: 2
    GeneSilico Metaserver: (Login and password: Jamboree)
    PDBBLAST: PDB: 2nx2_A SCOP: c.129.1.2
    FFAS: PDB: 2nx2_A SCOP: c.129.1.2
    MGENTHREADER: PDB: 2nx2_A SCOP: c.129.1.2
    BLASTP: PDB: 2nx2_A SCOP: c.129.1.2
    HHBLITS: PDB: 2nx2_A SCOP: c.129.1.2
    COMPASS: PDB: 2nx2_A SCOP: c.129.1.2
    CSBLAST: PDB: 2nx2_A SCOP: c.129.1.2
    HHSEARCH: PDB: 2nx2_A SCOP: c.129.1.2

    Topsan Members

    Tag pages as 'PF06908' to appear in this list.

    Name Annotation Author(s)


    Pfam family PFAM:PF06908 {Protein of unknown function (DUF1273) } with 101 members in NR database. The first structural representative solved (PDB Id: TOPSAN:2nx2) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1weha_ classified as Moco carrier protein-like fold. (Note: new fold solved by PSI). Profile-profile methods confirm remote homology between this family and superfamily of Moco carrier protein-like; fold of the same name. Based on remote homology confirmed by the structure one can hypothesize that this family is possible decarboxylales




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