The Open Protein Structure Annotation Network
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    Table of contents
    1. 1. Topsan Members
    2. 2. Summary
    3. 3. References

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    Pfam ID: DUF1260 PDB: 1nxi_A
    Solved by: NESG Priority Score: 1.6
    Member of this family is in PDB.
      # sequence matches: 473 # architectures: 4 # taxonomy ids:250
      Top FFAS hit in PDB: "1nxiA, conserved hypothetical protein VC0424" No significant hits in Pfam.
      Top significant hit (PDB90): "1nxiA, structural genomics, unknown function ; solution structure of vibrio cholerae protein vc0424 "
    CATH: CATH Domain E-value CATH Node
      1nxiA00 1.20E-29
      Publications(s) found: 389
      Publications(s) meeting filtering criteria: 11
    GeneSilico Metaserver: (Login and password: Jamboree)
    FFAS: PDB: 1nxi_A SCOP: d.58.47.1
    PHYRE: PDB: 1nxi_A SCOP: d.58.47.1
    MGENTHREADER: PDB: 1nxi_A SCOP: d.58.47.1
    PRC: PDB: 1nxi_A SCOP: d.58.47.1
    SPARKS: PDB: 1nxi_A SCOP: d.58.47.1
    HHBLITS: PDB: 1nxi_A SCOP: d.58.47.1
    COMPASS: PDB: 1nxi_A SCOP: d.58.47.1
    HHSEARCH: PDB: 1nxi_A SCOP: d.58.47.1
    E.coli Annotations
    NCBI: 16132077 PORTECO PORAL: rraB GeneExpDB: b4255

    Topsan Members

    Tag pages as 'PF06877' to appear in this list.

    Name Annotation Author(s)


    Pfam family PFAM:PF06877 {Protein of unknown function (DUF1260)} with 191 members in NR database and additional 25 members in the metagenomic datasets is represented in Bacteria. The first structural representative solved (PDB Id: TOPSAN:1nxi) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1j27a_ classified as Ferredoxin-like fold. However, no sequence similarity to this fold has been detected. Based on sequence and structure analysis/ original paper one can hypothesize that this family is could be involved in amino acid metabolic pathways such as that for arginine




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