.
The Open Protein Structure Annotation Network
PDB Keyword
.

PF06849

    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

    HTTP Status: UnableToConnect(0) (click for details)
    HTTP Status: UnableToConnect(0) (click for details)
      

    Resources
    Pfam ID: DUF1246 PDB: 2pbz_A
    Solved by: NYSGXRC Priority Score: 1.6
    Member of this family is in PDB.
    HMMER:
      # sequence matches: 137 # architectures: 1 # taxonomy ids:71
    FFAS:
      Top FFAS hit in PDB: "2r7kA, 5-formaminoimidazole-4-carboxamide-1-(beta)-D" No significant hits in Pfam.
    GRDB:
      Top significant hit (PDB90): "2r7kA, ligase ; crystal structure of faicar synthetase (purp) from m. jannaschii complexed with amppcp and aicar "
    CATH: CATH Domain E-value CATH Node
      2r85A01 1.90E-26 3.40.50.20
    FUNFAM (eval=0 ): 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase -like
    PUBSERVER:
      Publications(s) found: 73
      Publications(s) meeting filtering criteria: 3
    GeneSilico Metaserver: (Login and password: Jamboree)
    PDBBLAST: PDB: 2r7k_A SCOP: predicted d.142.1 ECC: 6.3.4.-
    FFAS: PDB: 2pbz_A SCOP: c.30.1.8 ECC: 6.3.4.-
    BLASTP: PDB: 2r7k_A SCOP: predicted d.142.1 ECC: 6.3.4.-
    HHBLITS: PDB: 2pbz_A SCOP: c.30.1.8 ECC: 6.3.4.-
    COMPASS: PDB: 2r7k_A SCOP: predicted d.142.1 ECC: 6.3.4.-
    CSBLAST: PDB: 2r7k_A SCOP: predicted d.142.1 ECC: 6.3.4.-
    HHSEARCH: PDB: 2pbz_A SCOP: c.30.1.8 ECC: 6.3.4.-

    Topsan Members

    Tag pages as 'PF06849' to appear in this list.

    Name Annotation Author(s)
    2pbz

    Summary

    Pfam family PFAM:PF06849 {Protein of unknown function (DUF1246)} with 175 members in NR database and additional 121 members in the metagenomic datasets is represented in Archaea, and Bacteria. The first structural representative solved (PDB Id: TOPSAN:2pbz) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1b6ra3 classified as preATP-grasp domain fold. Based on Ligand one can argue that this family is remotely homologous to previously known structures from 'd1b6ra3' this fold. Based on fold and evidence of homology, ligand one can hypothesize that this family is ligase; IMP biosynthesis protein PURP; protein is trimer with ATP in each monomer.

    Reviews

    References

     

    No references found.

    Tag page

    Files (0)

     
    You must login to post a comment.
    All content on this site is licensed under a Creative Commons Attribution 3.0 License
    Powered by MindTouch