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PF06824

    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

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    Resources
    Pfam ID: DUF1237 PDB: 2nvp_A
    Solved by: NESG Priority Score: 2.6
    Member of this family is in PDB.
    Member of this clan is in PDB.
    HMMER:
      # sequence matches: 538 # architectures: 10 # taxonomy ids:232
    FFAS:
      Top FFAS hit in PDB: "2p0vA, Hypothetical protein BT3781" Top FFAS hit in Pfam: "PF04853, Plant neutral invertase "
    GRDB:
      Top significant hit (PDB90): "2nvpA, structural genomics, unknown function ; crystal structure of the hypothetical protein cpf_0428 from clostridium perfringens, northeast structural genomics target cpr63. "
      Top significant hit (PFAM25U): "PF00723, Glycosyl hydrolases family 15"
    CATH: CATH Domain E-value CATH Node
      3cihA04 0.00017
      1gaiA00 0.00035 1.50.10.10
    FUNFAM (eval=0 ): Meiotically up-regulated gene 157 protein -like
    PUBSERVER:
      Publications(s) found: 203
      Publications(s) meeting filtering criteria: 1
    GeneSilico Metaserver: (Login and password: Jamboree)
    PDBBLAST: PDB: 3on6_A ECC: predicted 3.6.-.-
    FFAS: PDB: 2p0v_A SCOP: predicted a.102.1.4 ECC: predicted 3.6.-.-
    MGENTHREADER: PDB: 2nvp_A SCOP: a.102.1.8 ECC: predicted 2.8.-.-
    PRC: PDB: 1lf6_A SCOP: predicted a.102.1 ECC: 3.2.1.3
    BLASTP: PDB: 3on6_A ECC: predicted 3.6.-.-
    HHBLITS: PDB: 1ulv_A SCOP: predicted a.102.1 ECC: 3.2.1.70
    COMPASS: PDB: 2nvp_A SCOP: a.102.1.8 ECC: predicted 2.8.-.-
    COMA: PDB: 2p0v_A SCOP: predicted a.102.1.4 ECC: predicted 3.6.-.-
    CSBLAST: PDB: 3on6_A ECC: predicted 3.6.-.-
    HHSEARCH: PDB: 3p2c_A ECC: predicted 2.8.-.-

    Topsan Members

    Tag pages as 'PF06824' to appear in this list.

    Name Annotation Author(s)
    2nvp

    Summary

    Pfam family PFAM:PF06824 {Protein of unknown function (DUF1237) } with 162 members in NR database and additional 55 members in the metagenomic datasets is represented in Bacteria, and Eukaryota. The first structural representative solved (PDB Id: TOPSAN:2nvp) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1lf6a1 classified as Alpha/alpha toroid fold. Profile-profile methods confirm remote homology between this family and superfamily of Six-hairpin glycosidases; alpha/alpha toroid fold.

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