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PF06764

    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

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    Resources
    Pfam ID: DUF1223 PDB: 2axo_A
    Solved by: NESG Priority Score: 1.6
    Member of this family is in PDB.
    HMMER:
      # sequence matches: 256 # architectures: 6 # taxonomy ids:171
    FFAS:
      Top FFAS hit in PDB: "2axoA, hypothetical protein Atu2684" Top FFAS hit in Pfam: "PF11551, Outer membrane protein Omp28 "
    GRDB:
      Top significant hit (PDB90): "2axoA, unknown function ; crystal structure of the hypothetical protein agr_c_4864 from agrobacterium tumefaciens, nesg target atr35 "
      Top significant hit (PFAM25U): "PF11551, Outer membrane protein Omp28"
    CATH: CATH Domain E-value CATH Node
      1z3eA00 0.01
      3mszB00 0.0037 3.40.30.10
    PUBSERVER:
      Publications(s) found: 129
      Publications(s) meeting filtering criteria: 0
    GeneSilico Metaserver: (Login and password: Jamboree)
    PDBBLAST: PDB: 2axo_A SCOP: predicted c.47.1.19
    FFAS: PDB: 2axo_A SCOP: predicted c.47.1.19
    MGENTHREADER: PDB: 2axo_A SCOP: predicted c.47.1.19
    PRC: PDB: 2axo_A SCOP: predicted c.47.1.19
    BLASTP: PDB: 2axo_A SCOP: predicted c.47.1.19
    HHBLITS: PDB: 2axo_A SCOP: predicted c.47.1.19
    COMPASS: PDB: 2axo_A SCOP: predicted c.47.1.19
    CSBLAST: PDB: 2axo_A SCOP: predicted c.47.1.19
    HHSEARCH: PDB: 2axo_A SCOP: predicted c.47.1.19

    Topsan Members

    Tag pages as 'PF06764' to appear in this list.

    Name Annotation Author(s)
    2axo

    Summary

    Pfam family PFAM:PF06764 {Protein of unknown function (DUF1223) } with 127 members in NR database and additional 60 members in the metagenomic datasets is represented in Bacteria, and Eukaryota. The first structural representative solved (PDB Id: TOPSAN:2axo) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1fb6a_ classified as Two domains: thioredoxin fold and immunoglobulin-like beta-sandwich fold. Profile-profile methods confirm remote homology between this family and superfamily of Thioredoxin-like; thioredoxin fold. Based on remote homology confirmed by the structure one can hypothesize that this family is possible thioltransferase

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