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    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

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    Pfam ID: DUF1153 PDB: 2oa4_A
    Solved by: NESG Priority Score: 2.6
    Member of this family is in PDB.
    Member of this clan is in PDB.
      # sequence matches: 222 # architectures: 7 # taxonomy ids:163
      Top FFAS hit in PDB: "2oa4A, SiR5" Top FFAS hit in Pfam: "PF01527, Transposase "
      Top significant hit (PDB90): "2jrtA, structural genomics, unknown function ; nmr solution structure of the protein coded by gene rhos4_12090 of rhodobacter sphaeroides. northeast structural genomics target rhr5 "
      Top significant hit (PFAM25U): "PF01527, Transposase"
    CATH: CATH Domain E-value CATH Node
      2oa4A01 3.20E-28
      Publications(s) found: 101
      Publications(s) meeting filtering criteria: 4
    GeneSilico Metaserver: (Login and password: Jamboree)
    FFAS: PDB: 2oa4_A
    HHBLITS: PDB: 2jrt_A SCOP: predicted a.4.1.15
    COMPASS: PDB: 2jrt_A SCOP: predicted a.4.1.15
    HHSEARCH: PDB: 2oa4_A

    Topsan Members

    Tag pages as 'PF06627' to appear in this list.

    Name Annotation Author(s)


    Pfam family PFAM:PF06627 {Protein of unknown function (DUF1153) } with 66 members in NR database and additional 23 members in the metagenomic datasets is represented in Bacteria. The first structural representative solved (PDB Id: TOPSAN:2oa4) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1lvaa3 classified as DNA/RNA-binding 3-helical bundle fold. Profile-profile methods confirm remote homology between this family and superfamily of Homeodomain-like; DNA/RNA-binding 3-helical bundle fold. Based on remote homology confirmed by the structure one can hypothesize that this family is DNA-binding




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