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PF06267

    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

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    Resources
    Pfam ID: DUF1028 PDB: 2imh_A
    Solved by: NYSGXRC Priority Score: 2.6
    Member of this family is in PDB.
    Co-occurence with annotated domain(s) (no restrictions on number of architectures).
    HMMER:
      # sequence matches: 279 # architectures: 6 # taxonomy ids:192
    FFAS:
      Top FFAS hit in PDB: "2imhA, Hypothetical protein UNP Q5LQD5_SILPO" No significant hits in Pfam.
    GRDB:
      Top significant hit (PDB90): "2imhA, structural genomics, unknown function ; crystal structure of hypothetical protein from silicibacter pomeroyi "
    CATH: CATH Domain E-value CATH Node
      2imhA01 1.40E-77 3.60.20.10
    PUBSERVER:
      Publications(s) found: 171
      Publications(s) meeting filtering criteria: 0
    GeneSilico Metaserver: (Login and password: Jamboree)
    PDBBLAST: PDB: 2imh_A
    FFAS: PDB: 2imh_A
    MGENTHREADER: PDB: 2imh_A
    BLASTP: PDB: 2imh_A
    HHBLITS: PDB: 2imh_A
    COMPASS: PDB: 2imh_A
    COMA: PDB: 2imh_A
    CSBLAST: PDB: 2imh_A
    HHSEARCH: PDB: 2imh_A

    Topsan Members

    Tag pages as 'PF06267' to appear in this list.

    Name Annotation Author(s)
    2imh

    Summary

    Pfam family PFAM:PF06267 {Family of unknown function (DUF1028) } with 409 members in NR database and additional 350 members in the metagenomic datasets is represented in Archaea, and Bacteria. The first structural representative solved (PDB Id: TOPSAN:2imh) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1e94a_ classified as Ntn hydrolase-like fold. (Note: additional/lacking secondary structure elements). Based on prediction by HHpred (confirmed by the structure) links it to PF01112 that has Ntn hydrolase-like fold one can argue that this family is remotely homologous to previously known structures from 'd1e94a_' this fold.

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