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PF06108

    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

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    Pfam ID: DUF952 PDB: 2o0p_A
    Solved by: NESG Priority Score: 3.6
    Member of this family is in PDB.
    Co-occurence with annotated domain(s) (no restrictions on number of architectures).
    HMMER:
      # sequence matches: 388 # architectures: 13 # taxonomy ids:284
    FFAS:
      Top FFAS hit in PDB: "2jqnA, Hypothetical protein" No significant hits in Pfam.
    GRDB:
      Top significant hit (PDB90): "2jqnA, structural genomics ; solution nmr structure of cc0527 from caulobacter crescentus. northeast structural genomics target ccr55 "
    CATH: CATH Domain E-value CATH Node
      2jqnA00 1.10E-33
    PUBSERVER:
      Publications(s) found: 245
      Publications(s) meeting filtering criteria: 1
    GeneSilico Metaserver: (Login and password: Jamboree)
    PDBBLAST: PDB: 2o0q_A
    FFAS: PDB: 2o0p_A
    MGENTHREADER: PDB: 2o0q_A
    PRC: PDB: 2o0q_A
    BLASTP: PDB: 2o0q_A
    HHBLITS: PDB: 2o0q_A
    COMPASS: PDB: 2jqn_A SCOP: predicted d.166.1.7
    CSBLAST: PDB: 2o0q_A
    HHSEARCH: PDB: 2o0q_A

    Topsan Members

    Tag pages as 'PF06108' to appear in this list.

    Name Annotation Author(s)
    2o0p

    Summary

    Pfam family PFAM:PF06108 {Protein of unknown function (DUF952) } with 671 members in NR database and additional 570 members in the metagenomic datasets is represented in Archaea, Bacteria, and Eukaryota. The first structural representative solved (PDB Id: TOPSAN:2o0p) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1s5da_ classified as ADP-ribosylation fold. (Note: additional/lacking secondary structure elements). Based on prediction by HHpred (confirmed by the structure) links it to PF01885 that has ADP-ribosylation fold one can argue that this family is remotely homologous to previously known structures from 'd1s5da_' this fold.

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