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The Open Protein Structure Annotation Network
PDB Keyword
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PF05082

    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

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    Topsan Members

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    Name Annotation Author(s)
    2js5

    Summary

    Pfam family PFAM:PF05082 {Protein of unknown function (DUF683)} with 53 members in NR database and additional 5 members in the metagenomic datasets is represented in Bacteria. The first structural representative solved (PDB Id: TOPSAN:2js5) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1nkda_ classified as ROP-like fold. Profile-profile methods confirm remote homology between this family and superfamily of DHS-like NAD/FAD-binding domain; fold of the same name. Based on remote homology confirmed by the structure one can hypothesize that this family is signaling or transcription regulation

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