The Open Protein Structure Annotation Network
PDB Keyword


    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

    HTTP Status: UnableToConnect(0) (click for details)
    HTTP Status: UnableToConnect(0) (click for details)

    Topsan Members

    Tag pages as 'PF04672' to appear in this list.

    Name Annotation Author(s)
    The Tfu_2867 gene (PF04672, also known as DUF574) from Thermobifida fusca YX encodes the YP_290923 protein of unknown function. 2qe6 adopts a Rossman fold (2qe6-CATH). Pre-SCOP puts 2qe6 in the alpha... chrisx (3 edits)
    pascual (2 edits)


    Pfam family PFAM:PF04672 {Protein of unknown function (DUF574)} with 142 members in NR database and additional 1 members in the metagenomic datasets is represented in Bacteria. The first structural representative solved (PDB Id: TOPSAN:2qe6) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1rjda_ classified as S-adenosyl-L-methionine-dependent methyltransferase fold. Profile-profile methods confirm remote homology between this family and superfamily of S-adenosyl-L-methionine-dependent methyltransferases; fold of the same name. Based on remote homology confirmed by the structure, ligand one can hypothesize that this family is probably involved in transfer of methyl group




    No references found.

    Tag page

    Files (0)

    You must login to post a comment.
    All content on this site is licensed under a Creative Commons Attribution 3.0 License
    Powered by MindTouch