The Open Protein Structure Annotation Network
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    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

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    Pfam ID: DUF596 PDB: 2o5h_A
    Solved by: MCSG Priority Score: 1.6
    Member of this family is in PDB.
      # sequence matches: 81 # architectures: 1 # taxonomy ids:17
      Top FFAS hit in PDB: "2o5hA, Hypothetical protein" No significant hits in Pfam.
      Top significant hit (PDB90): "2o5hA, structural genomics, unknown function ; uncharacterized protein conserved in bacteria, cog3792 from neisseria meningitidis "
    CATH: CATH Domain E-value CATH Node
      2o5hA00 9.90E-25 1.10.3510.10
      Publications(s) found: 12
      Publications(s) meeting filtering criteria: 0
    GeneSilico Metaserver: (Login and password: Jamboree)
    PDBBLAST: PDB: 2o5h_A
    HHBLITS: PDB: 2o5h_A
    COMPASS: PDB: 2o5h_A
    CSBLAST: PDB: 2o5h_A
    HHSEARCH: PDB: 2o5h_A

    Topsan Members

    Tag pages as 'PF04591' to appear in this list.

    Name Annotation Author(s)


    Pfam family PFAM:PF04591 {Protein of unknown function, DUF596 } with 30 members in NR database. The first structural representative solved (PDB Id: TOPSAN:2o5h) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1cf7b_ classified as DNA/RNA-binding 3-helical bundle fold. (Note: additional/lacking secondary structure elements). However, no sequence similarity to this fold has been detected. Based on fold one can hypothesize that this family is probably binds nucleic acids




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