The Open Protein Structure Annotation Network
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    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

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    Pfam ID: DUF446 PDB: 2hgk_A
    Solved by: NESG Priority Score: 1.6
    Member of this family is in PDB.
      # sequence matches: 317 # architectures: 2 # taxonomy ids:174
      Top FFAS hit in PDB: "2hgkA, Hypothetical protein yqcC" No significant hits in Pfam.
      Top significant hit (PDB90): "2hgkA, structural genomics, unknown function ; solution nmr structure of protein yqcc from e. coli: northeast structural genomics consortium target er225 "
    CATH: CATH Domain E-value CATH Node
      2hgkA01 9.10E-41 1.20.1440.40
      Publications(s) found: 373
      Publications(s) meeting filtering criteria: 1
    GeneSilico Metaserver: (Login and password: Jamboree)
    FFAS: PDB: 2hgk_A
    HHBLITS: PDB: 2hgk_A
    COMPASS: PDB: 2hgk_A
    HHSEARCH: PDB: 2hgk_A
    E.coli Annotations
    NCBI: 16130699 PORTECO PORAL: yqcC GeneExpDB: b2792

    Topsan Members

    Tag pages as 'PF04287' to appear in this list.

    Name Annotation Author(s)


    Pfam family PFAM:PF04287 {Domain of unknown function, DUF446 } with 142 members in NR database and additional 33 members in the metagenomic datasets is represented in Bacteria. The first structural representative solved (PDB Id: TOPSAN:2hgk) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1v9va1 classified as Bromodomain-like fold. However, no sequence similarity to this fold has been detected.




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