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    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

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    Pfam ID: DUF305 PDB: 2qf9_A
    Solved by: NYSGXRC Priority Score: 3.6
    Member of this family is in PDB.
    Member of this clan is in PDB.
      # sequence matches: 998 # architectures: 9 # taxonomy ids:394
      Top FFAS hit in PDB: "2qf9A, Putative secreted protein" Top FFAS hit in Pfam: "PF13628, Domain of unknown function (DUF4142) "
      Top significant hit (PDB90): "3bt5A, structural genomics, unknown function ; crystal structure of duf305 fragment from deinococcus radiodurans "
      Top significant hit (PFAM25U): "PF13628, Domain of unknown function (DUF4142)"
    CATH: CATH Domain E-value CATH Node
      2qf9A01 2.10E-19 1.20.1260.10
      Publications(s) found: 257
      Publications(s) meeting filtering criteria: 2
    GeneSilico Metaserver: (Login and password: Jamboree)
    PDBBLAST: PDB: 2qf9_A SCOP: predicted a.25.1.1
    FFAS: PDB: 2qf9_A SCOP: predicted a.25.1.1
    MGENTHREADER: PDB: 3bt5_A SCOP: predicted a.25.1.4
    BLASTP: PDB: 2qf9_A SCOP: predicted a.25.1.1
    COMPASS: PDB: 2qf9_A SCOP: predicted a.25.1.1
    CSBLAST: PDB: 2qf9_A SCOP: predicted a.25.1.1
    HHSEARCH: PDB: 2qf9_A SCOP: predicted a.25.1.1

    Topsan Members

    Tag pages as 'PF03713' to appear in this list.

    Name Annotation Author(s)


    Pfam family PFAM:PF03713 {Domain of unknown function (DUF305)} with 1019 members in NR database and additional 702 members in the metagenomic datasets is represented in Bacteria, and Viruses. The first structural representative solved (PDB Id: TOPSAN:2qf9) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1lkoa1 classified as Ferritin-like fold. Based on marginal prediction from FFAS confirmed by structural similarity one can argue that this family is remotely homologous to previously known structures from 'd1lkoa1' this fold. Based on existing annotations enhanced by fold and evidence of homology one can hypothesize that this family is ferritin secreted by bacteria ?




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