The Open Protein Structure Annotation Network
PDB Keyword


    Table of contents
    1. 1. Topsan Members
    2. 2. Summary
    3. 3. References

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    Topsan Members

    Tag pages as 'PF03671' to appear in this list.

    Name Annotation Author(s)


    Pfam family PFAM:PF03671 {Uncharacterized protein family (UPF0185) } with 65 members in NR database and additional 2 members in the metagenomic datasets is represented in Eukaryota. The first structural representative solved (PDB Id: TOPSAN:1l7y) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1c1yb_ classified as Beta-Grasp (ubiquitin-like) fold. Based on marginal prediction from FFAS confirmed by structural similarity one can argue that this family is remotely homologous to previously known structures from 'd1c1yb_' this fold. Based on sequence and structure analysis/ original paper one can hypothesize that this family is may interact with an unidentified activating enzyme in a new ubiquitin-like modification system




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