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PF03193

    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

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    Resources
    Pfam ID: DUF258 PDB: 1t9h_A
    Solved by: non-psi Priority Score: 4.6
    Member of this family is in PDB.
    Member of this clan is in PDB.
    Co-occurence with annotated domain(s) (no restrictions on number of architectures).
    HMMER:
      # sequence matches: 19598 # architectures: 180 # taxonomy ids:1669
    FFAS:
      Top FFAS hit in PDB: "1t9hA, Probable GTPase engC" Top FFAS hit in Pfam: "PF05049, Interferon-inducible GTPase (IIGP) "
    GRDB:
      Top significant hit (PDB90): "1t9hA, hydrolase ; the crystal structure of yloq, a circularly permuted gtpase. "
      Top significant hit (PFAM25U): "PF01926, 50S ribosome-binding GTPase"
    CATH: CATH Domain E-value CATH Node
      1xewX00 0.0091
      2h92A00 0.01 3.40.50.300
      1qhlA00 2.20E-06 3.40.1140.10
      1t9hA03 6.90E-18 1.10.40.50
    FUNFAM (eval=0 ): Nitric oxide synthase 1 -like
    PUBSERVER:
      Publications(s) found: 1333
      Publications(s) meeting filtering criteria: 32
    GeneSilico Metaserver: (Login and password: Jamboree)
    PDBBLAST: PDB: 2rcn_A SCOP: predicted c.37.1.8 ECC: 3.6.1.-
    FFAS: PDB: 1t9h_A SCOP: predicted c.37.1 ECC: 3.6.1.-
    MGENTHREADER: PDB: 2rcn_A SCOP: predicted c.37.1.8 ECC: 3.6.1.-
    PRC: PDB: 1mky_A SCOP: predicted c.37.1
    SPARKS: PDB: 1t9h_A SCOP: predicted c.37.1 ECC: 3.6.1.-
    BLASTP: PDB: 2rcn_A SCOP: predicted c.37.1.8 ECC: 3.6.1.-
    HHBLITS: PDB: 1t9h_A SCOP: predicted c.37.1 ECC: 3.6.1.-
    COMPASS: PDB: 2rcn_A SCOP: predicted c.37.1.8 ECC: 3.6.1.-
    COMA: PDB: 2rcn_A SCOP: predicted c.37.1.8 ECC: 3.6.1.-
    CSBLAST: PDB: 2rcn_A SCOP: predicted c.37.1.8 ECC: 3.6.1.-
    HHSEARCH: PDB: 1t9h_A SCOP: predicted c.37.1 ECC: 3.6.1.-
    E.coli Annotations
    NCBI: 90111696 PORTECO PORAL: rsgA GeneExpDB: b4161

    Topsan Members

    Tag pages as 'PF03193' to appear in this list.

    No TOPSAN member(s) found.

    Summary

    Members of this family all contain sequence motifs typical of the vast class of P-loop-containing GTPases, but show a circular permutation, with a G4-G1-G3 pattern of motifs as opposed to the regular G1-G3-G4 pattern seen in most GTPases 12220175.

     

    Note, this family should be extend top cover the complete domain, which is currently split due to the circular permutation.

     

    Reviews

    References

     

    No references found.

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