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PF01989

    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

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    Resources
    Pfam ID: DUF126 PDB: 2hi6_A
    Solved by: NESG Priority Score: 2.6
    Member of this family is in PDB.
    Member of this clan is in PDB.
    HMMER:
      # sequence matches: 198 # architectures: 3 # taxonomy ids:149
    FFAS:
      Top FFAS hit in PDB: "2hi6A, UPF0107 protein AF0055" No significant hits in Pfam.
    GRDB:
      Top significant hit (PDB90): "2hi6A, structural genomics, unknown function ; solution nmr structure of upf0107 protein af_0055, northeast structural genomics consortium target gr101 "
    CATH: CATH Domain E-value CATH Node
      2hi6A00 5.50E-34 3.50.30.10
    PUBSERVER:
      Publications(s) found: 139
      Publications(s) meeting filtering criteria: 0
    GeneSilico Metaserver: (Login and password: Jamboree)
    PHYRE: PDB: 2hi6_A SCOP: c.8.2.3
    MGENTHREADER: PDB: 2hi6_A
    PRC: PDB: 2hi6_A
    HHBLITS: PDB: 2hi6_A
    COMPASS: PDB: 2hi6_A
    HHSEARCH: PDB: 2hi6_A

    Topsan Members

    Tag pages as 'PF01989' to appear in this list.

    Name Annotation Author(s)
    2hi6

    Summary

    Pfam family

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    {Protein of unknown function DUF126 } with 257 members in NR database and additional 187 members in the metagenomic datasets is represented in Archaea, Bacteria, and Eukaryota. The first structural representative solved (PDB Id:
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    ) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain
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    classified as The "swivelling" beta/beta/alpha domain fold. (Note: additional/lacking secondary structure elements). Profile-profile methods confirm remote homology between this family and superfamily of Phosphohistidine domain; the "swivelling" beta/beta/alpha domain fold. Based on remote homology confirmed by the structure one can hypothesize that this family is phosphotransferase

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