The Open Protein Structure Annotation Network
PDB Keyword


    Table of contents
    1. 1. Topsan Members
    2. 2. Summary

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    Topsan Members

    Tag pages as 'PF01987' to appear in this list.

    Name Annotation Author(s)


    Pfam family PFAM:PF01987 {Protein of unknown function DUF124} with 498 members in NR database and additional 223 members in the metagenomic datasets is represented in Archaea, Bacteria, and Eukaryota. The first structural representative solved (PDB Id: TOPSAN:1pg6) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1dzra_ classified as Double-stranded beta-helix fold. Based on prediction by HHpred (confirmed by the structure) links it to PF02041 that has Double-stranded beta-helix fold one can argue that this family is remotely homologous to previously known structures from 'd1dzra_' this fold. Based on existing annotations enhanced by structural similarity one can hypothesize that this family is binds nucleic acids, possibly RNA




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